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Analysis of gene expression patterns in brown adipose tissue

GSE269003 Mus musculus Expression profiling by high throughput sequencing 4 samples Submitted 2024/07/22 Platform GPL13112
Summary
Brown adipose tissue is a specialized fat tissue involved in heat generation by using a process termed thermogenesis. This ability to convert nutrient energy into heat sets brown adipocytes apart from the more common type of white adipocytes, which are mainly involved in energy storage. Brown adipose depots occur as a large interscapular depot in mice. Brown adipocytes are multilocular, i.e. contain many small lipid-filled vacuoles and uniquely express the uncoupling protein 1. In this study, the gene expression patterns in brown adipose tissue samples of young, healthy mice was analyzed.
Published in
Adipocyte deletion of the oxygen-sensor PHD2 sustains elevated energy expenditure at thermoneutrality
Wang R, Gomez Salazar M, Pruñonosa Cervera I et al. · Nature communications 2024 · PMID 39209825 · doi:10.1038/s41467-024-51718-7
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Direct links to NCBI, no account and no request form: the whole study as GSE269003_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 4 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1119934 and SRA study SRP511614. Searching any of these in the dataset finder brings you back here.

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