YAP1 is a key regulator of EWS::FLI1-dependent malignant transformation upon IGF-1 mediated reprogramming of bone mesenchymal stem cells [ATAC-seq]
ChIP-seq / ATAC-seq (genome binding and open chromatin) · mouse · 12 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Mus musculus (mouse)
- Samples
- 12 samples: 10 distinct titles, 2 of them repeatedGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- YAP1 is a key regulator of EWS::FLI1-dependent malignant transformation upon IGF-1-mediated reprogramming of bone mesenchymal stem cellsCell reports · 2025
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE269004_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA1119935 and SRA study SRP511604. Searching any of these in the dataset finder brings you back here.
How we read this: Read from 12 sample titles: 10 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8304724 S_220_1
- GSM8304725 S_221_1
- GSM8304726 WT_1_1
- GSM8304727 WT_2_1
- GSM8304728 BM_unt
- GSM8304729 BM_IGF1
- GSM8304730 S_203_0
- GSM8304731 S_220_0
- GSM8304732 S_221_0
- GSM8304733 S_220_IGF1
- GSM8304734 S_221_IGF1
- GSM8304735 S_221_IGF1_xeno
- GSE269007 YAP1 is a key regulator of EWS::FLI1-dependent malignant transformation upon IGF-1 mediated reprogramming of bone mesenchymal stem cells 27 samples shares igf-1, yap1, ews, fli1-dependent, transformation, reprogramming, mesenchymal, regulator
- GSE269006 YAP1 is a key regulator of EWS::FLI1-dependent malignant transformation upon IGF-1 mediated reprogramming of bone mesenchymal stem cells [RNA-seq] 15 samples shares igf-1, yap1, ews, fli1-dependent, transformation, reprogramming, mesenchymal, regulator
- GSE281696 Sustained YAP1 signaling alters the fate of lutein and Müllerian mesenchymal cells in mice 8 samples shares yap1, mesenchymal
- GSE287795 YAP1-TFE3 mediates endothelial to mesenchymal transition in epithelioid hemangioendothelioma 7 samples shares yap1, mesenchymal
- GSE223111 Sex differences in Yap1 oncogene function in immune evasion [ChIP-seq] 6 samples shares yap1
- GSE260811 Cooperative super-enhancer inactivation caused by heterozygous loss of CREBBP and KMT2D skews B-cell fate decisions and accelerates development of T-cell depleted lymphomas [Mint-ChIP] 6 samples shares ews
- GSE274533 ZMAT1 promotes osteoclast formation and bone loss through TRIM46 mediated YAP1 degradation. [CUT&Tag] 2 samples shares yap1
- GSE303415 RNA Sequencing of Liver and Skeletal Muscle from WT and Heterozygous IGF-1R Mutant Mice 48 samples shares igf-1
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.