Effect of melatonin during LPS-induced inflammation on RAW 264.7 cells
RNA-seq (gene expression) · mouse · 36 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 36 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Melatonin alleviates high-fat-diet-induced dry eye by regulating macrophage polarization via IFT27 and lowering ERK/JNK phosphorylationiScience · 2024
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE269343_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1121248 and SRA study SRP512430. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 36 more — browse all 36 samples with per-sample file links →
- GSE262688 Effect of knockout of Samsn1 on gene expression during E.coli infection in Raw264.7 cells 12 samples shares raw
- GSE252232 Effect of Lcn2 on gene expression during osteoclast differentiation of RAW 264.7 cells in the presence of Cpn60 treatment 9 samples shares raw
- GSE227237 Effect of chaperonin 60 kDa on gene expression during osteoclast differentiation of RAW 264.7 cells 6 samples shares raw
- GSE290919 Transcriptome analysis of Kdm7a-deficient RAW264.7 cells during macrophage polarization. 18 samples shares raw
- GSE207257 Effect of STING-TRIM29 interaction inhibitor SB24011 on gene expression upon solo or co-treatment with STING agonist in Raw264.7 murine macrophage-like cells. 18 samples shares raw
- GSE287433 Effects of Tirzepatide on macrophage polarization, inflammatory factors and atherosclerotic genes in RAW264.7 cells under oxidative low-density lipoprotein 16 samples shares raw
- GSE236340 Effect of loperamide on transcriptional profile of Raw264.7 cells infected with Salmonella 12 samples shares raw
- GSE278583 Effect of Drp1 inhibitor on gene expression profiles of RAW264.7 cells at 24 hours or 96 hours after LPS and IFN-γ stimulation 12 samples shares raw
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.