GEO series
Effect of knockout of Samsn1 on gene expression during E.coli infection in Raw264.7 cells
GSE262688
Mus musculus
Expression profiling by high throughput sequencing
12 samples
2025/06/01
GPL24247
Summary
In sepsis, infection and immunosuppression occur simultaneously. We currently found that Samsn1 expression is increased on myeloid cells in sepsis. And, Samsn1 is currently recognized as a negative regulator of immune response. So we constructed Samsn1 knockout Raw264.7 cells to study the effect of Samsn1 on macrophage function and the gene expression of macrophages with infection.
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