Effect of Drp1 inhibitor on gene expression profiles of RAW264.7 cells at 24 hours or 96 hours after LPS and IFN-γ stimulation
RNA-seq (gene expression) · mouse · 12 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 12 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE278583_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1167868 and SRA study SRP536124. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 12 more — browse all 12 samples with per-sample file links →
- GSE282271 Global transcriptional profiles of mouse intestinal organoids treated with IFN-g or/and MEK inhibitor [RNA-Seq] 26 samples shares ifn, inhibitor, profiles
- GSE318498 Gene expression differences between LPS, anti-CD36 Abs, or LPS plus anti-CD36 Abs treated RAW264.7 cells. 12 samples shares raw264, lps
- GSE201128 The response to lipopolysaccharide (LPS) of bone marrow derived macrophages treated with oxysterol binding protein (OSBP) inhibitors 30 samples shares lps, inhibitor
- GSE297320 The mRNA levels of Ly6G+ cells from the bone marrow of septic mice after IFN-gamma stimulation. 30 samples shares ifn, stimulation
- GSE196249 Secondary LPS stimulation of BMDMs differentiated from bone marrow of C57B/6J mice treated with 4xLPS, 1xLPS or PBS 18 samples shares lps, stimulation
- GSE262107 Next Generation Sequencing to identify the differential expression genes of murine lung tissues upon the stimulation of LPS with/without recombinant TSLP pretreatment 10 samples shares lps, stimulation
- GSE21764 To determine the global gene expression response in murine LPS-induced macrophages treated with a bromodomain inhibitor. 24 samples shares lps, inhibitor
- GSE326200 Absence of Clec1a in murine cDC1s decrease IFN responses to necrotic cells 237 samples shares ifn
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.