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Deciphering the Divergent Transcriptomic Landscapes of Cervical Cancer Cells Grown in 3D and 2D Cell Culture Systems

GSE270674 Homo sapiens Expression profiling by high throughput sequencing 8 samples Submitted 2024/09/13 Platform GPL24676
Summary
Cervical cancer remains a significant health challenge for women worldwide, with a disproportionate impact on developing regions like sub-Saharan Africa. Taking advantage of recent advancements in developing suitable preclinical models to study cell proliferation, differentiation, and gene expression, we used RNA sequencing to compare the transcriptomic profiles of SiHa cervical cancer cells grown in 3D versus 2D culture systems.
Published in
Deciphering the divergent transcriptomic landscapes of cervical cancer cells grown in 3D and 2D cell culture systems
Kumar R, Iden M, Tsaih SW et al. · Frontiers in cell and developmental biology 2024 · PMID 39193365 · doi:10.3389/fcell.2024.1413882
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Direct links to NCBI, no account and no request form: the whole study as GSE270674_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 8 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1127667 and SRA study SRP515697. Searching any of these in the dataset finder brings you back here.

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