Differentially Expressed Genes in C-33A and CaSki Cells Overexpressing miR-124-3p, miR-23b-3p, or miR-218-5p Modulate Processes and Pathways Involved in Cervical Cancer Progression
RNA-seq (gene expression) · human · 23 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Topic
- Cervical cancerThis series is part of our curated briefing on it.
- Samples
- 23 samples: 18 distinct titles, 5 of them repeatedGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE279412_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1172670 and SRA study SRP545509. Searching any of these in the dataset finder brings you back here.
How we read this: Read from 23 sample titles: 18 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8569522 C33ARB1_Sc
- GSM8569523 C33ARB2_Sc
- GSM8569524 C33ARB3_Sc
- GSM8569525 C33ARB2_miR124
- GSM8569526 C33ARB3_miR124
- GSM8569527 C33ARB1_miR23b
- GSM8569528 C33ARB2_miR23b
- GSM8569529 C33ARB3_miR23b
- GSM8569530 C33ARB1_miR218
- GSM8569531 C33ARB2_miR218
- GSM8569532 C33ARB3_miR218
- GSM8569533 CaSkiRB1_Sc
- GSM8569534 CaSkiRB2_Sc
- GSM8569535 CaSkiRB3_Sc
- GSM8569536 CaSkiRB1_miR124
- GSM8569537 CaSkiRB2_miR124
- GSM8569538 CaSkiRB3_miR124
- GSM8569539 CaSkiRB1_miR23b
- GSM8569540 CaSkiRB2_miR23b
- GSM8569541 CaSkiRB3_miR23b
- GSM8569542 CaSkiRB1_miR218
- GSM8569543 CaSkiRB2_miR218
- GSM8569544 CaSkiRB3_miR218
- GSE289927 Overexpression of miR-23b-3b+miR-218-5p+miR-124-3p differentially modifies the transcriptome of C-33A and CaSki cells and the regulation of cellular processes involved in the progression of cervical cancer 12 samples same disease briefing · shares mir-124-3p, mir-218-5p, c-33a, differentially, progression
- GSE253690 Identification of differentially expressed genes in tumorigenesis of cervical cancer via next generation sequencing 6 samples same disease briefing · shares differentially, expressed
- GSE306495 Elevated VAMP8 Expression Promotes Cervical Cancer Progression by Enhancing Autophagy via HIF-1 Pathway 12 samples same disease briefing · shares progression
- GSE326407 EPHB2 Drives EMT-Linked Vasculogenic Mimicry and Cervical Cancer Progression via an ERK–ETV4 Transcriptional Program 9 samples same disease briefing · shares progression
- GSE297095 ADAR1 expression is associated with cervical cancer progression and negatively regulates NK cell activity 8 samples same disease briefing · shares progression
- GSE316098 Spatial Transcriptomic Landscape of Invasion Patterns in Human Papillomavirus-Associated Endocervical Adenocarcinoma 186 samples same disease briefing
- GSE303300 Neoadjuvant Immune Checkpoint Blockade Before Chemoradiation for Patients with FIGO Stage IB3–IVA Cervical Squamous Carcinoma: GINECO Window-Of-Opportunity COLIBRI Study 96 samples same disease briefing
- GSE168244 Patient-derived organoids as a platform to study cervical cancer and viral infection 36 samples same disease briefing
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.