GEO series
mTOR Signaling Regulates Multiple Metabolic Pathways in Human Lung Fibroblasts After TGF-β and in Pulmonary Fibrosis
GSE270973
Homo sapiens
Expression profiling by high throughput sequencing
28 samples
2024/12/12
GPL20301
Summary
We investigated the effects of mTOR and ATF4 on gene expression in human lung fibroblasts using RNA-sequencing. We found both ATF4 and mTOR regulate expression of genes that are involved in controlling amino acid synthesis and transportation. mTOR additionally regulates genes that are involved in glycolysis and oxidative phosphorylation.
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Paper (PMID 39745695) ↗
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