← BioTransfer GEO Dataset Finder
GEO series

The role of GPR43 in regulating asthmatic lung eosinophils

GSE271832 Mus musculus Expression profiling by high throughput sequencing 9 samples Submitted 2025/09/24 Platform GPL17021
Summary
GPR43 is a short-chain fatty acid receptor exerting anti-inflammatory functions in various inflammatory diseases. Even though eosinophils are one of the cell types highly expressing GPR43, the role of GPR43 in regulating eosinophils has not been studied. In this experiment, we compared transcriptomic profiles of control (Epx-Cre/+) and GPR43-deficient (Epx-Cre/+GPR43fl/fl) eosinophils purified from asthmatic lungs using bulk RNA sequencing.
Published in
GPR43 in eosinophils suppresses the emergence of pathogenic Siglec-F(hi) neutrophils in allergic airway inflammation in mice
Yu J, Kim S, Song HS et al. · Nature communications 2025 · PMID 41298412 · doi:10.1038/s41467-025-65573-7
This dataset
Download

Direct links to NCBI, no account and no request form: the whole study as GSE271832_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 9 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1133708 and SRA study SRP518873. Searching any of these in the dataset finder brings you back here.

Samples in this study

The sample list for this study is not cached yet. Press Sort into groups and it will be fetched from NCBI.

+ 9 more — browse all 9 samples with per-sample file links →

Similar datasets

Search all mouse RNA-seq datasets in GEO →

Share this dataset

Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.