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Adipocyte induced distinct gene expression profiling of human endometrioid endometrial cancer cells upon SIRT1 inhibition.

GSE272263 Homo sapiens Expression profiling by high throughput sequencing 5 samples Submitted 2024/08/05 Platform GPL20301
Summary
We examined the mechanism by which adiposity regulates endometrioid endometrial cancer progression. Ishikawa EEC cells were co-cultured with mature adipocytes in presence or absence of SIRT1 inhibitor EX527, and total RNA was isolated for RNA-seq analysis and focus on the functional relevance that adipocyte co-culture affected pathways and related biomarkers may have in endometrial cancer response to adiposity.
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Also filed as BioProject PRJNA1132979 and SRA study SRP518989. Searching any of these in the dataset finder brings you back here.

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