GEO series
Adverse proinflammatory responses in the kidney after FGF23 administration in murine kidney disease models
GSE272289
Mus musculus
Expression profiling by high throughput sequencing
38 samples
2025/07/15
GPL30172
Summary
FGF23 is a biomarker associated with morbidity and mortality, but controversies remain if a causative link exists between FGF23 excess and adverse renal consequences in chronic kidney disease (CKD). Here, we investigated renal FGF23 signaling in kidney disease models in mice, with a focus on adverse pro-inflammatory effects assessed in bulk transcriptomes.
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Paper (PMID 41744000) ↗
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