AOS10-FMT could rescure the adverse effects induced by high fat diet on the kidney
RNA-seq (gene expression) · mouse · 18 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 18 samples: 6 conditions, mostly in triplicateGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE173566_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA726169 and SRA study SRP316890. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 18 samples.
How we read this: 6 replicated groups read from 18 sample titles; they account for 18 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM5270922 kidney A10-1 kidney A10
- GSM5270923 kidney A10-2 kidney A10
- GSM5270924 kidney A10-3 kidney A10
- GSM5270925 kidney con-1 kidney con
- GSM5270926 kidney con-2 kidney con
- GSM5270927 kidney con-3 kidney con
- GSM5270928 kidney HFD-1 kidney HFD
- GSM5270929 kidney HFD-2 kidney HFD
- GSM5270930 kidney HFD-3 kidney HFD
- GSM5270931 kidney HA10-1 kidney HA10
- GSM5270932 kidney HA10-2 kidney HA10
- GSM5270933 kidney HA10-3 kidney HA10
- GSM5270934 kidney HAF-1 kidney HAF
- GSM5270935 kidney HAF-2 kidney HAF
- GSM5270936 kidney HAF-3 kidney HAF
- GSM5270937 kidney HCF-1 kidney HCF
- GSM5270938 kidney HCF-2 kidney HCF
- GSM5270939 kidney HCF-3 kidney HCF
- GSE315007 Sex- and hepatocyte Pparg-dependent hepatic effects of a high fat diet containing 60% kcal from fat and 2% cholesterol, which was supplemented with 10% fructose in the drinking water (HFC+Fr) to induce diet-induced obesity in male and female mice. 30 samples shares induced, diet
- GSE329539 Hypothalamic transcriptomic response to High-Fat Diet induced obesity: modulatory effects of Resveratrol, Curcumin, and Aged Garlic Extract. 12 samples shares induced, diet
- GSE267751 Time-restricted feeding prevents memory impairments induced by obesogenic diet consumption in mice, in part through hippocampal thyroid hormone signaling. 71 samples shares induced, diet
- GSE302447 A multi-functional oral small molecule targeting energy and lipid metabolism as a treatment for diet-induced obesity 67 samples shares induced, diet
- GSE262523 Diet-Induced Obesity Disrupts Sexually Dimorphic Gene Expression in Liver and Adipose Tissue in Mice 48 samples shares induced, diet
- GSE292815 Diet-induced phospholipid remodeling dictates ferroptosis sensitivity and tumorigenesis in the pancreas 39 samples shares induced, diet
- GSE252343 Hofbauer cells and fetal brain microglia share transcriptional profiles and responses to maternal diet-induced obesity 34 samples shares induced, diet
- GSE307265 Experimentally induced myocardial infarction in mice - RNA Sequencing of kidneys 24 samples shares induced, kidney
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.