FGF23 partial agonism improves rhabdomyolysis-induced acute kidney injury
RNA-seq (gene expression) · mouse · 12 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 12 samples: 4 × AKI_A_FGF23_R176QR179Q vs 4 × AKI_A_mcherry vs 4 × NCGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE326953_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1447989 and SRA study SRP689176. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 12 samples.
How we read this: 3 replicated groups read from 12 sample titles; they account for 12 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM9644283 AKI_A_FGF23_R176QR179Q_1 AKI_A_FGF23_R176QR179Q
- GSM9644284 AKI_A_FGF23_R176QR179Q_2 AKI_A_FGF23_R176QR179Q
- GSM9644285 AKI_A_FGF23_R176QR179Q_3 AKI_A_FGF23_R176QR179Q
- GSM9644286 AKI_A_FGF23_R176QR179Q_5 AKI_A_FGF23_R176QR179Q
- GSM9644287 AKI_A_mcherry_1 AKI_A_mcherry
- GSM9644288 AKI_A_mcherry_2 AKI_A_mcherry
- GSM9644289 AKI_A_mcherry_3 AKI_A_mcherry
- GSM9644290 AKI_A_mcherry_4 AKI_A_mcherry
- GSM9644291 NC_1 NC
- GSM9644292 NC_2 NC
- GSM9644293 NC_3 NC
- GSM9644294 NC_4 NC
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- GSE310628 NBL1 Associates with Renal Phenotypes in Mice, but Partial Nbl1 Reduction Does Not Ameliorate Kidney Disease: Male Nbl1 HET or WT Mice Treated with Cisplatin or PBS 31 samples shares partial, kidney
- GSE294969 Enhanced Expression of the Female-Biased Gene Gsta2 in Male Proximal Tubule Cells Improves Renal Resilience to Ischemia-Reperfusion Injury 30 samples shares improves, injury
- GSE297353 Steroid hormone antagonism reduces the rate of aortic rupture and improves survival in a mouse model of Vascular Ehlers-Danlos Syndrome 30 samples shares improves, agonism
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- GSE294923 Nfkb1 removal from proximal tubule cells improves renal tubular outcomes following ischemia reperfusion injury 14 samples shares improves, injury
- GSE282210 Transcriptome analysis of quiescent livers and regenerating livers after partial hepatectomy (PH) in young and aged mice 133 samples shares partial
- GSE325237 Higher basal tumor immune activity coupled with a systemic immune response improves liver cancer outcomes 116 samples shares improves
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.