Jinhua Hecha-a fermented green tea improves sleep via regulating glutamatergic synapses and gut microbiota
RNA-seq (gene expression) · mouse · 18 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 18 samples: 18 samples, each with a distinct title — no replicated groupsGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE272388_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1136549 and SRA study SRP520315. Searching any of these in the dataset finder brings you back here.
Any grouping that defines a comparison lives in the sample characteristics, which GEO records separately from the titles.
How we read this: Read from 18 sample titles: 18 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8399832 NCC_2,Colon tissue, administered saline for 44 days
- GSM8399833 ,NCC_8Colon tissue, administered saline for 44 days
- GSM8399834 NCC_17,Colon tissue, administered saline for 44 days
- GSM8399835 NCX_124,Colon tissue, administered saline for 44 days
- GSM8399836 NCX_134,Colon tissue, administered saline for 44 days
- GSM8399837 NCX_147,Colon tissue, administered saline for 44 days
- GSM8399838 FFZRC_5,Colon tissue was intragastric administration of compound Suanzoren capsule for 44 days
- GSM8399839 FFZRC_12,Colon tissue was intragastric administration of compound Suanzoren capsule for 44 days
- GSM8399840 FFZRC_24,Colon tissue was intragastric administration of compound Suanzoren capsule for 44 days
- GSM8399841 FFZRX_139,Colon tissue was intragastric administration of compound Suanzoren capsule for 44 days
- GSM8399842 FFZRX_238,Colon tissue was intragastric administration of compound Suanzoren capsule for 44 days
- GSM8399843 FFZRX_268,Colon tissue was intragastric administration of compound Suanzoren capsule for 44 days
- GSM8399844 JHHCGC_7,Colon tissue, intragastric administration of Jinhua Hecha-a fermented green tea for 44 days
- GSM8399845 JHHCGC_19,Colon tissue, intragastric administration of Jinhua Hecha-a fermented green tea for 44 days
- GSM8399846 JHHCGC_48,Colon tissue, intragastric administration of Jinhua Hecha-a fermented green tea for 44 days
- GSM8399847 JHHCGX_129,Colon tissue, intragastric administration of Jinhua Hecha-a fermented green tea for 44 days
- GSM8399848 JHHCGX_148,Colon tissue, intragastric administration of Jinhua Hecha-a fermented green tea for 44 days
- GSM8399849 JHHCGX_256JHHCGX,Colon tissue, intragastric administration of Jinhua Hecha-a fermented green tea for 44 days
- GSE191016 Planar cell polarity proteins mediate ketamine-induced restoration of glutamatergic synapses in prefrontal cortical neurons in a mouse model for chronic stress 20 samples shares glutamatergic, synapses
- GSE291933 Sensory neurons drive pancreatic cancer progression through glutamatergic cancer-neuron pseudo-synapses 12 samples shares glutamatergic, synapses
- GSE302208 Regional encoding of enteric nervous system responses to microbiota and type 2 inflammation [Neuron SmartSeq2] 169 samples shares microbiota
- GSE300428 Rbm24 promotes outer hair cell survival through Insm1 repression while independently regulating hair bundle morphogenesis 163 samples shares regulating
- GSE287225 Laboratory mice engrafted with natural gut microbiota possess a wildling-like phenotype 160 samples shares microbiota
- GSE216620 Gut microbiota dysbiosis rewires host mRNA m6A epitranscriptomic landscape via bile acid metabolism 102 samples shares microbiota
- GSE293180 Analysis of Host and Microbiome Responses to Antibiotics Reveals Microbiota-Independent Effects on Gut Immune Response [multiabx] 97 samples shares microbiota
- GSE260491 Microbiota of infants consuming secretors or non-secretors mothers milk impacts gut and immune system in mice. 83 samples shares microbiota
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.