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Effect of depletion of FAM129B on gene expression during skeletal muscle differentiation of C2C12 cells

GSE273604 Mus musculus Expression profiling by high throughput sequencing 8 samples Submitted 2025/06/01 Platform GPL34290
Summary
Muscle atrophy, a decline in muscle mass and quantity caused by a variety of factors such as cancer, aging, and long-term use of glucocorticoids, manifested at the molecular level as excessive protein catabolism. Muscle atrophy severely affects the quality of life and the treatment remains an unresolved challenge. FAM129B is an antioxidant protein that plays a key role in signal transduction.FAM129B has previously been reported to be involved in muscle growth and development in cattle. The current study aims to describe the role of FAM129B in muscle atrophy, which is expected to be a potential therapeutic target for skeletal muscle atrophy.
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Also filed as BioProject PRJNA1142493 and SRA study SRP523525. Searching any of these in the dataset finder brings you back here.

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