TICRR/TRESLIN and MTBP Cut&Run in G1 synchronized HCT 116 cells
ChIP-seq / ATAC-seq (genome binding and open chromatin) · human · 30 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Homo sapiens (human)
- Samples
- 30 samples: 12 conditions, mostly in triplicateGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Cell cycle-dependent TICRR/TRESLIN and MTBP chromatin binding mechanisms and patternsGenome biology · 2025
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE274464_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA1146462 and SRA study SRP525458. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 30 samples.
How we read this: 12 replicated groups read from 30 sample titles; they account for 30 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8449646 Cycling_HCT116_GFP_replicate1 Cycling_HCT116_GFP
- GSM8449647 Cycling_HCT116_GFP_replicate2 Cycling_HCT116_GFP
- GSM8449648 Cycling_HCT116_GFP_replicate3 Cycling_HCT116_GFP
- GSM8449649 Cycling_HCT116_IgG_50_replicate2 Cycling_HCT116_IgG_50
- GSM8449650 Cycling_HCT116_IgG_50_replicate3 Cycling_HCT116_IgG_50
- GSM8449651 Cycling_MTBP_GFP_replicate1 Cycling_MTBP_GFP
- GSM8449652 Cycling_MTBP_GFP_replicate2 Cycling_MTBP_GFP
- GSM8449653 Cycling_MTBP_GFP_replicate3 Cycling_MTBP_GFP
- GSM8449654 Cycling_MTBP_IgG_50_replicate2 Cycling_MTBP_IgG_50
- GSM8449655 Cycling_MTBP_IgG_50_replicate3 Cycling_MTBP_IgG_50
- GSM8449656 Cycling_TICRR_GFP_replicate1 Cycling_TICRR_GFP
- GSM8449657 Cycling_TICRR_GFP_replicate2 Cycling_TICRR_GFP
- GSM8449658 Cycling_TICRR_GFP_replicate3 Cycling_TICRR_GFP
- GSM8449659 Cycling_TICRR_IgG_50_replicate2 Cycling_TICRR_IgG_50
- GSM8449660 Cycling_TICRR_IgG_50_replicate3 Cycling_TICRR_IgG_50
- GSM8449661 G1_HCT116_GFP_replicate1 G1_HCT116_GFP
- GSM8449662 G1_HCT116_GFP_replicate2 G1_HCT116_GFP
- GSM8449663 G1_HCT116_GFP_replicate3 G1_HCT116_GFP
- GSM8449664 G1_HCT116_IgG_50_replicate2 G1_HCT116_IgG_50
- GSM8449665 G1_HCT116_IgG_50_replicate3 G1_HCT116_IgG_50
- GSM8449666 G1_MTBP_GFP_replicate1 G1_MTBP_GFP
- GSM8449667 G1_MTBP_GFP_replicate2 G1_MTBP_GFP
- GSM8449668 G1_MTBP_GFP_replicate3 G1_MTBP_GFP
- GSM8449669 G1_MTBP_IgG_50_replicate2 G1_MTBP_IgG_50
- GSM8449670 G1_MTBP_IgG_50_replicate3 G1_MTBP_IgG_50
- GSM8449671 G1_TICRR_GFP_replicate1 G1_TICRR_GFP
- GSM8449672 G1_TICRR_GFP_replicate2 G1_TICRR_GFP
- GSM8449673 G1_TICRR_GFP_replicate3 G1_TICRR_GFP
- GSM8449674 G1_TICRR_IgG_50_replicate2 G1_TICRR_IgG_50
- GSM8449675 G1_TICRR_IgG_50_replicate3 G1_TICRR_IgG_50
- GSE274463 TICRR/TRESLIN and MTBP Cut&Run in Asynchronously Cycling HCT116 Cells 27 samples shares treslin, ticrr, mtbp, hct
- GSE274465 TICRR/TRESLIN and MTBP Cut&Run in HCT116 cells with inhibited origin licensing 12 samples shares treslin, ticrr, mtbp, hct
- GSE294620 MTBP Cut&Run of FACS sorted cell cycle populations in HCT116 cells 10 samples shares mtbp, hct
- GSE293195 Regulated TRESLIN-MTBP loading governs initiation zones and replication timing in human DNA replication [ChIP-Seq] 46 samples shares treslin, mtbp
- GSE293196 Regulated TRESLIN-MTBP loading governs initiation zones and replication timing in human DNA replication [IP-seq] 8 samples shares treslin, mtbp
- GSE293200 Regulated TRESLIN-MTBP loading governs initiation zones and replication timing in human DNA replication [RNA-Seq] 6 samples shares treslin, mtbp
- GSE324343 Analysis of ER stress-induced three-dimensional enhancer network in wild-type and transcription facotr-knockout HCT116 cells [ChIP-Seq] 94 samples shares hct
- GSE276857 CUT&Tag in K562, HCT116, RPE1 and Jurkat cells 39 samples shares hct
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.