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Combination of MEK and Autophagy Inhibition in the preclinical GEMM model of PDAC (KPC mice)

GSE274516 Mus musculus Expression profiling by high throughput sequencing 6 samples Submitted 2026/06/17 Platform GPL24247
Summary
In order to investigate the mechiansim of action and the effect of the combination of MEK/Autophagy Inhibition on pancreatic tumors, KPC mice were treated with Vehicle or combination of Trametinib and Hydroxychloroquine for 24 hours. PDAC tumors were collected and single cell suspension was subjected to single-cell RNA-Sequencing analysis.
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Also filed as BioProject PRJNA1146933 and SRA study SRP525725. Searching any of these in the dataset finder brings you back here.

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