H4K16 acylations fine-tune transcriptional response during metabolic perturbations (ChIP-seq)
ChIP-seq / ATAC-seq (genome binding and open chromatin) · mouse · 46 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Mus musculus (mouse)
- Samples
- 46 samples: 46 samples, each with a distinct title — no replicated groupsGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- H4K16 acylations destabilize chromatin architecture and facilitate transcriptional response during metabolic perturbationsMolecular cell · 2026
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE275933_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA1153613 and SRA study SRP529210. Searching any of these in the dataset finder brings you back here.
Any grouping that defines a comparison lives in the sample characteristics, which GEO records separately from the titles.
How we read this: Read from 46 sample titles: 46 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8488295 fWT1A_input
- GSM8488296 fWT2A_input
- GSM8488297 fPA1A_input
- GSM8488298 fPA2A_input
- GSM8488299 fWT1A_H3K27ac
- GSM8488300 fWT2A_H3K27ac
- GSM8488301 fPA1A_H3K27ac
- GSM8488302 fPA2A_H3K27ac
- GSM8488303 fWT1A_H3K9ac
- GSM8488304 fWT2A_H3K9ac
- GSM8488305 fPA1A_H3K9ac
- GSM8488306 fPA2A_H3K9ac
- GSM8488307 fWT1A_H4K16ac
- GSM8488308 fWT2A_H4K16ac
- GSM8488309 fPA1A_H4K16ac
- GSM8488310 fPA2A_H4K16ac
- GSM8488311 fWT1A_H4K16bu
- GSM8488312 fWT2A_H4K16bu
- GSM8488313 fPA1A_H4K16bu
- GSM8488314 fPA2A_H4K16bu
- GSM8488315 fWT1B_input
- GSM8488316 fWT2B_input
- GSM8488317 fPA1B_input
- GSM8488318 fPA2B_input
- GSM8488319 fWT1B_TermoH4K16pr
- GSM8488320 fWT2B_TermoH4K16pr
- GSM8488321 fPA1B_TermoH4K16pr
- GSM8488322 fPA2B_TermoH4K16pr
- GSM8488323 fWT1B_Nr5H4K16pr
- GSM8488324 fWT2B_Nr5H4K16pr
- GSM8977170 fWT1B_H4K5ac
- GSM8977171 fWT2B_H4K5ac
- GSM8977172 fPA1B_H4K5ac
- GSM8977173 fPA2B_H4K5ac
- GSM8977174 fPA2B_H4K5pr
- GSM8977175 fWT1B_H4K5pr
- GSM8977176 fWT1B_H4K12ac
- GSM8977177 fWT1B_H4K12pr
- GSM8977178 fWT2B_H4K5pr
- GSM8977179 fWT2B_H4K12ac
+ 6 more — browse all 46 samples with per-sample file links →
- GSE275932 H4K16 acylations fine-tune transcriptional response during metabolic perturbations (ATAC-seq) 4 samples shares h4k16, perturbations, acylations, fine-tune
- GSE296977 H4K16 acylations fine-tune transcriptional response to short-chain acyl-CoA dehydrogenase deficiency (ChIP-seq) 24 samples shares h4k16, acylations, fine-tune, chip-seq
- GSE275934 H4K16 acylations fine-tune transcriptional response during metabolic perturbations (RNA-seq) 4 samples shares h4k16, perturbations, acylations, fine-tune
- GSE296976 H4K16 acylations fine-tune transcriptional response to short-chain acyl-CoA dehydrogenase deficiency (ATAC-seq) 8 samples shares h4k16, acylations, fine-tune
- GSE296978 H4K16 acylations fine-tune transcriptional response to short-chain acyl-CoA dehydrogenase deficiency (RNA-seq) 6 samples shares h4k16, acylations, fine-tune
- GSE227727 Mecp2 fine-tunes quiescence exit by targeting nuclear receptors [ChIP-Seq] 8 samples shares fine-tune, chip-seq
- GSE304211 H4K16ac contributes to chromatin compartment reorganization during mitotic and meiotic transitions [CUTnTAG] 128 samples shares h4k16
- GSE248650 Nicotinamide Mononucleotide Promotes Female Germline Stem Cell Proliferation by Activating the H4K16ac-Hmgb1-Fyn-PLD Signaling Pathway through Epigenetic Remodeling 8 samples shares h4k16
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.