GEO series
Transcriptional profiling of cDC2 subsets in IFNAR∆CD11c mice treated with allergens
GSE276029
Mus musculus
Expression profiling by high throughput sequencing
24 samples
2025/07/21
GPL30172
Summary
Conventional type 2 Dendritic Cells (cDC2) in the skin are cell subsets primarily responsible for the priming of T-helper type 2 (TH2) responses in the draining LN. The local inflammatory milieu has been demonstrated to condition cDC2 to promote such responses. To characterise the cDC2 response to the cytokine IFN-I, we performed bulk RNAseq on sorted cDC2 subsets from IFNAR∆CD11c and IFNARWT mice following treatment with an allergen.
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Paper (PMID 40462316) ↗
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