EOMES safeguards TSC chromatin accessibility by directing BRG1 to TSC-associated loci [RNA-seq]
RNA-seq (gene expression) · mouse · 45 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 45 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Eomesodermin in conjunction with the BAF complex promotes expansion and invasion of the trophectoderm lineageNature communications · 2025
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE276261_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1156180 and SRA study SRP530291. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 45 more — browse all 45 samples with per-sample file links →
- GSE276039 EOMES safeguards TSC chromatin accessibility by directing BRG1 to TSC-associated loci [ATAC-seq] 36 samples shares eomes, brg1, tsc, tsc-associated, accessibility, safeguards, chromatin, directing
- GSE276042 EOMES safeguards TSC chromatin accessibility by directing BRG1 to TSC-associated loci [CUT&RUN] 6 samples shares eomes, brg1, tsc, tsc-associated, accessibility, safeguards, chromatin, directing
- GSE156569 BRG1 contributes to the global chromatin accessibility revealed by its acute depletion 102 samples shares brg1, accessibility, chromatin
- GSE271610 The chromatin remodeler Brg1 is essential for cochlear sensory epithelium differentiation and patterning 7 samples shares brg1, chromatin
- GSE272547 EOMES establishes mesoderm and endoderm differentiation potential through SWI/SNF-mediated global enhancer remodeling [RNA-Seq] 49 samples shares eomes
- GSE338265 Smad4 and Eomes converge on a shared transcriptional program associated with inflammatory CD8 T-cell differentiation 31 samples shares eomes
- GSE300734 Brg1 defect causes aberrent nucleosome landscape and affects totipotency & pluripotency transcriptional factors binding during embryogenesis [RNA-seq] 25 samples shares brg1
- GSE245062 Eomes expression identifies the early bone marrow precursor to classical NK cells 23 samples shares eomes
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.