Effect of modulation of microRNA-455-3p on gene expression in SW1353 human chondrosarcoma cells
RNA-seq (gene expression) · human · 12 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 12 samples: 12 samples, each with a distinct title — no replicated groupsGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- The microRNA-455 null mouse shows dysregulated bone turnoverJBMR plus · 2025
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE276347_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1156758 and SRA study SRP530487. Searching any of these in the dataset finder brings you back here.
Any grouping that defines a comparison lives in the sample characteristics, which GEO records separately from the titles.
How we read this: Read from 12 sample titles: 12 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8496829 SW1353 cells, miR-455 mimic control, 48 hours (1)
- GSM8496830 SW1353 cells, miR-455 mimic control, 48 hours (2)
- GSM8496831 SW1353 cells, miR-455 mimic control, 48 hours (3)
- GSM8496832 SW1353 cells, miR-455 mimic , 48 hours (1)
- GSM8496833 SW1353 cells, miR-455 mimic , 48 hours (2)
- GSM8496834 SW1353 cells, miR-455 mimic , 48 hours (3)
- GSM8496835 SW1353 cells, miR-455 inhibitor control , 48 hours (1)
- GSM8496836 SW1353 cells, miR-455 inhibitor control , 48 hours (2)
- GSM8496837 SW1353 cells, miR-455 inhibitor control , 48 hours (3)
- GSM8496838 SW1353 cells, miR-455 inhibitor , 48 hours (1)
- GSM8496839 SW1353 cells, miR-455 inhibitor , 48 hours (2)
- GSM8496840 SW1353 cells, miR-455 inhibitor , 48 hours (3)
- GSE261434 A personalized medicine approach identifies enasidenib as an efficient treatment for IDH2 mutant chondrosarcoma [RNAseq_Enasidenib_L2975_SW1353] 12 samples shares sw1353, chondrosarcoma
- GSE295784 Selective modulation of gene expression in activated normal human peripheral blood mononuclear cells by store-operated calcium entry blocker BTP2 40 samples shares modulation
- GSE313156 Temporal modulation of gene expression in a controlled Schistosoma mansoni human infection model 144 samples shares modulation
- GSE254862 Effect of ADAR1 and MDA5 knock down by siRNA on human SMC phenotypic modulation and calcification in vitro 42 samples shares modulation
- GSE287081 Modulation of predicted key driver genes of an atherosclerosis-associated gene regulatory network in human endothelial cells 24 samples shares modulation
- GSE316025 Feeder-free generation of CD4 single-positive helper T cells from human iPSCs via stage-specific modulation of Notch and TCR Signaling 21 samples shares modulation
- GSE279593 BMP, MEK and WNT modulation with NGN2 expression for rapid neuron differentiation from hiPSC amenable to regional patterning 158 samples shares modulation
- GSE296931 PGR Isoform Modulation via Enhancer Activation Regulates Progesterone Signaling in Human Endometrial Stromal Cells [RNA-Seq] 18 samples shares modulation
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.