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p53 binds to the regulatory regions of dsRNA-containing genes in 2153L tumor cells

GSE276358 Mus musculus Genome binding/occupancy profiling by high throughput sequencing 4 samples Submitted 2024/10/16 Platform GPL24247
Summary
We analyzed the genome-wide p53 binding profile in 2153L tumor cells. We found p53 binds to the regulatory regions of dsRNAs-containing genes. our result suggests that p53 may directly repress the expression of these genes.
Published in
IRE1α silences dsRNA to prevent taxane-induced pyroptosis in triple-negative breast cancer
Xu L, Peng F, Luo Q et al. · Cell 2024 · PMID 39419025 · doi:10.1016/j.cell.2024.09.032
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Also filed as BioProject PRJNA1156778 and SRA study SRP530493. Searching any of these in the dataset finder brings you back here.

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