Sex-specific molecular signature of mouse podocytes in homeostasis and in response to pharmacological challenge with rapamycin
RNA-seq (gene expression) · mouse · 20 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 20 samples: 6 × female_rapa vs 5 × male_rapa vs 5 × female_vehicle vs 4 × male_vehicleGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Sex-specific molecular signature of mouse podocytes in homeostasis and in response to pharmacological challenge with rapamycinBiology of sex differences · 2024
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE276967_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1159842 and SRA study SRP532145. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 20 samples.
How we read this: 4 replicated groups read from 20 sample titles; they account for 20 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8510453 male_rapa_233 male_rapa
- GSM8510454 male_rapa_252 male_rapa
- GSM8510455 male_rapa_312 male_rapa
- GSM8510456 male_rapa_319 male_rapa
- GSM8510457 female_rapa_323 female_rapa
- GSM8510458 male_rapa_347 male_rapa
- GSM8510459 female_rapa_315 female_rapa
- GSM8510460 female_rapa_316 female_rapa
- GSM8510461 female_rapa_322 female_rapa
- GSM8510462 female_rapa_326 female_rapa
- GSM8510463 female_rapa_336 female_rapa
- GSM8510464 male_vehicle_308 male_vehicle
- GSM8510465 male_vehicle_313 male_vehicle
- GSM8510466 male_vehicle_317 male_vehicle
- GSM8510467 male_vehicle_344 male_vehicle
- GSM8510468 female_vehicle_318 female_vehicle
- GSM8510469 female_vehicle_324 female_vehicle
- GSM8510470 female_vehicle_334 female_vehicle
- GSM8510471 female_vehicle_339 female_vehicle
- GSM8510472 female_vehicle_340 female_vehicle
- GSE325494 Pharmacological inhibition of GLUT1 alleviates fulminant hepatitis by restraining macrophage-induced inflammatory cascades and restoring metabolic homeostasis 9 samples shares pharmacological, homeostasis
- GSE255212 Transcriptomic Signatures of WNT-Driven Pathways and Granulosa Cell-Oocyte Interaction during Primordial Follicle Activation 762 samples shares signature
- GSE300176 Molecular Signatures and Signaling Interactions of the Hair Follicle Stem Cell Niche 56 samples shares signature
- GSE291420 Deciphering the Transcriptomic Signatures of Aging Across Organs in Mice 270 samples shares signature
- GSE318028 Pharmacological inhibition of FKBP51 mitigates early life adversity-induced social deficits 246 samples shares pharmacological
- GSE254229 ALS/FTD-linked TBK1 deficiency in microglia induces an aged-like microglial signature and drives social recognition deficits in mice 141 samples shares signature
- GSE300534 Brain Mecp2 Genetic Dosage and Gene Therapy Shape Multi-omics Signatures and Biomarkers in Rett Syndrome [1] 137 samples shares signature
- GSE300536 Brain Mecp2 Genetic Dosage and Gene Therapy Shape Multi-omics Signatures and Biomarkers in Rett Syndrome [2] 137 samples shares signature
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.