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Gene expression profiling by RNA-seq of control and TRIM21-knockdownHCT8 cells

GSE276995 Homo sapiens Expression profiling by high throughput sequencing 6 samples Submitted 2025/09/12 Platform GPL20795
Summary
In order to define the cohort of genes whose expression is regulated by TRIM21 in CRC, we constructed HCT8 cells stably infected with lentivirus carrying control shRNA (shNC) or TRIM21 shRNA (sh1). Subsequently, total RNA was isolated and then performed transcriptome RNA sequence.
Published in
TRIM21 promotes colorectal cancer development through regulating DNA replication by TCF3/MCM2/5 axis
Zhang X, Yao H, Hou Y et al. · Cell death discovery 2025 · PMID 40998798 · doi:10.1038/s41420-025-02722-3
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Also filed as BioProject PRJNA1160180 and SRA study SRP532270. Searching any of these in the dataset finder brings you back here.

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