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Gene expression profile at single cell level of primary neuronal culture from cortices of C57Bl6 and hTau mice treated with pathogenic brain-derived Tau oligomers

GSE277105 Mus musculus Expression profiling by high throughput sequencing 8 samples Submitted 2025/01/22 Platform GPL21626
Summary
Primary cortical neurons are established tool to study Tau oligomers-mediated toxicity. We used single-cell RNA seq to identify diverisity of gene expression upon Tau oligomers treatment
Published in
Brain-derived tau oligomer polymorphs: distinct aggregations, stability profiles, and biological activities
Lo Cascio F, Park S, Sengupta U et al. · Communications biology 2025 · PMID 39809992 · doi:10.1038/s42003-025-07499-w
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Also filed as BioProject PRJNA1160803 and SRA study SRP532505. Searching any of these in the dataset finder brings you back here.

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