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Evaluation of the impact of genetically suppression of Nupr1 in aged vs young type 2 alveolar epithelial cells (AT2).

GSE277203 Mus musculus Expression profiling by high throughput sequencing 6 samples Submitted 2024/09/25 Platform GPL24247
Summary
Our data demonstrated that Nupr1 has an age-specific function in the proliferation and differentiation of lung adenocarcinoma cells that are derived from AT2 cells. However, how Nupr1 impact AT2 cells in vivo has not been tested. Using somatic genetic approaches, we performed single-cell mRNA sequencing with primary AT2 cells with control or shRNAs targeting Nupr1.
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Direct links to NCBI, no account and no request form: the whole study as GSE277203_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 6 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1161177 and SRA study SRP532755. Searching any of these in the dataset finder brings you back here.

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