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CSF1R marks a subset of foetal LMPPs with Acute Myeloid Leukaemia propagation properties in a KMT2A-MLLT3 mouse model

GSE277342 Mus musculus Expression profiling by high throughput sequencing 7 samples Submitted 2025/11/25 Platform GPL30172
Summary
As KMT2A-MLLT3 oncoprotein can give rise to ALL and AML in infants, we investigated whether such choice could lie in two subsets of foetal LMPPs, that express or not CSF1R, and found that CSF1R mark a more potent subpopulation with leukaemic-initiating
Published in
CSF1R marks a subset of foetal haematopoietic multipotent progenitor cells with acute myeloid leukaemia propagation properties
Camiolo G, González Silvera D, Leah T et al. · Leukemia 2026 · PMID 41545699 · doi:10.1038/s41375-025-02856-4
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Also filed as BioProject PRJNA1161855 and SRA study SRP533046. Searching any of these in the dataset finder brings you back here.

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