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RNA-seq profiling of CD34-high and CD34-low fibroblasts from mouse mammary tumors

GSE277526 Mus musculus Expression profiling by high throughput sequencing 6 samples Submitted 2025/07/22 Platform GPL19057
Summary
A mouse model of Wnt1-driven mammary tumors was generated. Specifically, PdfraH2B-GFP mice (C57BL/6) were crossed to MMTV-cre(A)-Wnt1 transgenic mice (FVB/J) to generate the raGFP-Wnt1 mouse line. CD34-high and CD34-low fibroblast cells were then FACS sorted from mammary tumors from the raGFP-Wnt1 mice.
Published in
Fibroblast hierarchy dynamics during mammary gland morphogenesis and tumorigenesis
Pascual R, Cheng J, De Smet AH et al. · The EMBO journal 2025 · PMID 40216939 · doi:10.1038/s44318-025-00422-3
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Also filed as BioProject PRJNA1162645 and SRA study SRP533467. Searching any of these in the dataset finder brings you back here.

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