Innate tissue immunosurveillance by γδ T cells has real-time dependence on the T cell receptor [RNA-seq]
RNA-seq (gene expression) · mouse · 23 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 23 samples: 6 conditions, mostly in triplicateGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE277903_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1164729 and SRA study SRP534481. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 19 samples.
How we read this: 6 replicated groups read from the first 19 of 23 sample titles; they account for 19 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8534218 Epidermis_WT_rep1 Epidermis_WT
- GSM8534219 Epidermis_WT_rep2 Epidermis_WT
- GSM8534220 Epidermis_WT_rep4 Epidermis_WT
- GSM8534221 Epidermis_TCR_KO_rep1 Epidermis_TCR_KO
- GSM8534222 Epidermis_TCR_KO_rep2 Epidermis_TCR_KO
- GSM8534223 Epidermis_TCR_KO_rep3 Epidermis_TCR_KO
- GSM8534225 Dermis_WT_rep1 Dermis_WT
- GSM8534226 Dermis_WT_rep2 Dermis_WT
- GSM8534227 Dermis_WT_rep4 Dermis_WT
- GSM8534228 Dermis_TCR_KO_rep1 Dermis_TCR_KO
- GSM8534229 Dermis_TCR_KO_rep2 Dermis_TCR_KO
- GSM8534231 Dermis_TCR_KO_rep4 Dermis_TCR_KO
- GSM8534232 Gut_WT_rep1 Gut_WT
- GSM8534233 Gut_WT_rep2 Gut_WT
- GSM8534234 Gut_WT_rep3 Gut_WT
- GSM8534235 Gut_TCR_KO_rep1 Gut_TCR_KO
- GSM8534236 Gut_TCR_KO_rep2 Gut_TCR_KO
- GSM8534237 Gut_TCR_KO_rep3 Gut_TCR_KO
- GSM8534239 Gut_TCR_KO_rep5 Gut_TCR_KO
+ 4 more — browse all 23 samples with per-sample file links →
- GSE256409 Antibody Fc-receptor common gamma chain FcεR1γ stabilizes cell surface receptors in group 3 innate lymphoid cells and promotes anti-infection immunity 20 samples shares receptor, innate
- GSE291710 Macrophages expressing Macrophage Receptor with Collagen Structure Attenuate Liver Fibrosis Through a Tissue Restoration Phenotype [macrophage_liverFibrosis_scRNA-seq] 10 samples shares receptor, rna-seq
- GSE266438 Loss of Sphingosine-1-Phosphate Receptor 4 weakens innate mechanisms leading to defective lymph node hypertrophy and germinal center formation 45 samples shares receptor, innate
- GSE306262 Astrocyte glucocorticoid receptor signaling restricts neuronal plasticity [RNA-seq] 40 samples shares receptor, rna-seq
- GSE325918 Nuclear receptor Nur77 resolves the inflammatory response of macrophages primarily by regulating expression of AP-1 transcription factors and their target genes [RNA-seq] 32 samples shares receptor, rna-seq
- GSE294805 Effect of cardiomyocyte-specific activation of nuclear receptor subfamily 4 group A member 2 (NR4A2) on poly(A) RNA expression profile in the mouse heart [RNA-seq] 32 samples shares receptor, rna-seq
- GSE319597 Lineage identity governs oncogene dependence in murine NSCLC models of KRAS inhibitor resistance [RNA-Seq] 16 samples shares dependence, rna-seq
- GSE244342 Activated-ATF6α is an ER stress-inducing oncoprotein metabolically restricting immunosurveillance [bulk RNA-seq of TG-AAV-GFP/CRE, DEN/HFD] 16 samples shares immunosurveillance, rna-seq
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.