Expression profiles of human cumulus cells from patients with PCOS and non-PCOS
RNA-seq (gene expression) · human · 40 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 40 samples: 23 × PCOS vs 17 × ControlGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Multi-omics approach to reveal follicular metabolic changes and their effects on oocyte competence in PCOS patientsFrontiers in endocrinology · 2024
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE277906_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1164742 and SRA study SRP534488. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 40 samples.
How we read this: 2 replicated groups read from 40 sample titles; they account for 40 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8534278 Control1 Control
- GSM8534279 Control2 Control
- GSM8534280 Control3 Control
- GSM8534281 Control4 Control
- GSM8534282 Control5 Control
- GSM8534283 Control6 Control
- GSM8534284 Control7 Control
- GSM8534285 Control8 Control
- GSM8534286 Control9 Control
- GSM8534287 Control10 Control
- GSM8534288 Control11 Control
- GSM8534289 Control12 Control
- GSM8534290 Control13 Control
- GSM8534291 Control14 Control
- GSM8534292 Control15 Control
- GSM8534293 Control16 Control
- GSM8534294 Control17 Control
- GSM8534295 PCOS1 PCOS
- GSM8534296 PCOS2 PCOS
- GSM8534297 PCOS3 PCOS
- GSM8534298 PCOS4 PCOS
- GSM8534299 PCOS5 PCOS
- GSM8534300 PCOS6 PCOS
- GSM8534301 PCOS7 PCOS
- GSM8534302 PCOS8 PCOS
- GSM8534303 PCOS9 PCOS
- GSM8534304 PCOS10 PCOS
- GSM8534305 PCOS11 PCOS
- GSM8534306 PCOS12 PCOS
- GSM8534307 PCOS13 PCOS
- GSM8534308 PCOS14 PCOS
- GSM8534309 PCOS15 PCOS
- GSM8534310 PCOS16 PCOS
- GSM8534311 PCOS17 PCOS
- GSM8534312 PCOS18 PCOS
- GSM8534313 PCOS19 PCOS
- GSM8534314 PCOS20 PCOS
- GSM8534315 PCOS21 PCOS
- GSM8534316 PCOS22 PCOS
- GSM8534317 PCOS23 PCOS
- GSE271704 5G-exposed human skin cells do not respond with altered gene expression and methylation profiles [RNA-Seq] 120 samples shares profiles
- GSE266239 Single Cell Sequencing of Human Langerhans Cells Identifies Altered Gene Expression Profiles in Patients with Atopic Dermatitis 13 samples shares profiles
- GSE224698 Gene expression profiles of human dermal fibroblasts and human pluripotent stem cells analyzed by bulk RNA-seq 69 samples shares profiles
- GSE250127 Gene expression profiles under oxidative stress conditions in human HaCaT keratinocytes and the derivative cells expressing shRNA against NRF2, MLL1, or UTX. 12 samples shares profiles
- GSE243370 Gene expression profiles of human iPSC-derived microglia in monoculture and in co-culture with isogenic iPSC-derived neural cells 12 samples shares profiles
- GSE271961 Integrated electrophysiological and genomic profiles of single cells reveal spiking tumor cells in human glioma [Patch-Seq] 95 samples shares profiles
- GSE254569 Gene expression profiles at single-cell level of human post-mortem brain tissue from the orbitofrontal cortex 92 samples shares profiles
- GSE294621 Vascular-type heterogeneity is associated with differential gene expression profiles of endothelial cells under shear stress 74 samples shares profiles
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.