Platelets induce endothelial cell mitochondrial dysfunction in myocardial infarction
RNA-seq (gene expression) · human · 52 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 52 samples: 48 distinct titles, 2 of them repeatedGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Platelets induce endothelial cell mitochondrial dysfunction in myocardial infarctionScience advances · 2025
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE278026_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1165249 and SRA study SRP534751. Searching any of these in the dataset finder brings you back here.
How we read this: Read from 52 sample titles: 48 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8538086 PBS-1
- GSM8538087 PBS-2
- GSM8538088 PBS-3
- GSM8538089 PBS-4
- GSM8538090 CCL3 100-1
- GSM8538091 CCL3 100-2
- GSM8538092 HARP-01-0002-1
- GSM8538093 HARP-01-0031-1
- GSM8538094 HARP-01-0036-1
- GSM8538095 HARP-01-0049-1
- GSM8538096 HARP-01-0058-1
- GSM8538097 HARP-01-0114-1
- GSM8538098 HARP-01-0173-1
- GSM8538099 HARP-01-0184-1
- GSM8538100 HARP-01-0231-1
- GSM8538101 HARP-01-0242-1
- GSM8538102 HARP-01-0244-1
- GSM8538103 HARP-01-0033-1
- GSM8538104 HARP-01-0034-1
- GSM8538105 HARP-01-0035-1
- GSM8538106 HARP-01-0039-1
- GSM8538107 HARP-01-0043-1
- GSM8538108 HARP-01-0057-1
- GSM8538109 HARP-01-0174-1
- GSM8538110 HARP-01-0177-1
- GSM8538111 HARP-01-0204-1
- GSM8538112 HARP-01-0236-1
- GSM8538113 HARP-01-0243-1
- GSM8538114 HARP-01-0245-1
- GSM8538115 HARP-01-0246-1
- GSM8538116 HARP-01-5003-1
- GSM8538117 HARP-01-5015-1
- GSM8538118 HARP-01-5016-1
- GSM8538119 HARP-01-5026-1
- GSM8538120 HARP-01-5028-1
- GSM8538121 HARP-01-5035-1
- GSM8538122 HARP-01-5040-1
- GSM8538123 HARP-01-5044-1
- GSM8538124 HARP-01-5045-1
- GSM8538125 HARP-01-5047-1
+ 12 more — browse all 52 samples with per-sample file links →
- GSE343456 MCART1 (SLC25A51) deficiency exacerbates mitochondrial dysfunction during MPP+-induced complex I stress 24 samples shares mitochondrial, dysfunction, induce
- GSE237200 Endothelial transcription factor EB protects against doxorubicin-induced endothelial toxicity and cardiac dysfunction 20 samples shares endothelial, dysfunction, induce
- GSE327103 Glabridin Promotes Melanosome Degradation and Alleviates Melanosome-Induced Mitochondrial Dysfunction in Keratinocytes via Autophagy 9 samples shares mitochondrial, dysfunction, induce
- GSE253337 Mitochondrial anomalies in induced pluripotent stem cells from Alzheimer’s disease cases with Presenilin 1 mutation 36 samples shares mitochondrial, induce
- GSE296680 Using plasma cell-free mRNA to profile immune response and myocardial damage in immune checkpoint inhibitor-induced myocarditis 26 samples shares myocardial, induce
- GSE323983 Senescence inhibition by rapamycin mitigates radiation-induced atherosclerotic characteristics in human coronary endothelial cells 23 samples shares endothelial, induce
- GSE324673 Feeder-Free Generation of Lymphatic Endothelial Cells from Human Induced Pluripotent Stem Cells 15 samples shares endothelial, induce
- GSE269269 Single-Cell RNA Sequencing of Peripheral Blood Mononuclear Cells From Acute Myocardial Infarction 10 samples shares myocardial, infarction
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.