GEO series
Platelets induce endothelial cell mitochondrial dysfunction in myocardial infarction
GSE278026
Homo sapiens
Expression profiling by high throughput sequencing
52 samples
2025/08/29
GPL24676
Summary
Coronary endothelial dysfunction playsa key role in the pathogenesis of cardiovascular events. In the setting of myocardial infarction (MI), activatedplatelets release prothrombotic and proinflammatory factors, contributing to vascular injury and dysfunction.However, the effect of platelets on coronary endothelial function during MI is not fully understood. We investigated the effect of platelets from patients with MI on cultured coronary endothelial cells in vitro.
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Paper (PMID 41237248) ↗
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