GEO series
Cryptic splice sites generate heterogeneous EZH2 isoforms with distinct functions in embryonic development [CUT&Tag]
GSE278313
Mus musculus
Genome binding/occupancy profiling by high throughput sequencing
20 samples
2025/09/17
GPL24247
Summary
A novel Ezh2 variant was identified, we named Ezh2b, which is lost 27-nt region in the end of exon3, has different functions on embryonic development in mouse compared to Ezh2 with 27-nt region (namely as Ezh2a). Here, we apply transcriptome sequencing to explore the underlying molecular mechanisms.
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Paper (PMID 40923763) ↗
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