Gene expression differences between LPS, anti-CD36 Abs, or LPS plus anti-CD36 Abs treated RAW264.7 cells.
RNA-seq (gene expression) · mouse · 12 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 12 samples: 3 × RAW264.7, untreat, vs 3 × RAW264.7, Anti-CD36, vs 3 × RAW264.7, LPS, vs 3 × RAW264.7, LPS+Anti-CD36,Groups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE318498_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1419041 and SRA study SRP674801. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 12 samples.
How we read this: 4 replicated groups read from 12 sample titles; they account for 12 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM9496763 RAW264.7, untreat, rep1 RAW264.7, untreat,
- GSM9496764 RAW264.7, untreat, rep2 RAW264.7, untreat,
- GSM9496765 RAW264.7, untreat, rep3 RAW264.7, untreat,
- GSM9496766 RAW264.7, Anti-CD36, rep1 RAW264.7, Anti-CD36,
- GSM9496767 RAW264.7, Anti-CD36, rep2 RAW264.7, Anti-CD36,
- GSM9496768 RAW264.7, Anti-CD36, rep3 RAW264.7, Anti-CD36,
- GSM9496769 RAW264.7, LPS, rep1 RAW264.7, LPS,
- GSM9496770 RAW264.7, LPS, rep2 RAW264.7, LPS,
- GSM9496771 RAW264.7, LPS, rep3 RAW264.7, LPS,
- GSM9496772 RAW264.7, LPS+Anti-CD36, rep1 RAW264.7, LPS+Anti-CD36,
- GSM9496773 RAW264.7, LPS+Anti-CD36, rep2 RAW264.7, LPS+Anti-CD36,
- GSM9496774 RAW264.7, LPS+Anti-CD36, rep3 RAW264.7, LPS+Anti-CD36,
- GSE279383 Transcriptome profiles of RAW264.7 cells under fibroblast coculture with or without LPS sitimulation and tryptophan metabolites intervention 24 samples shares raw264, lps
- GSE325662 Gene expression profiling of lung tissue from LPS-induced acute lung injury mice treated with Renshen Baidu Powder 9 samples shares lps, treated
- GSE201128 The response to lipopolysaccharide (LPS) of bone marrow derived macrophages treated with oxysterol binding protein (OSBP) inhibitors 30 samples shares lps, treated
- GSE196249 Secondary LPS stimulation of BMDMs differentiated from bone marrow of C57B/6J mice treated with 4xLPS, 1xLPS or PBS 18 samples shares lps, treated
- GSE249970 Transcriptome analysis of lung derived from LPS-induced ARDS model mice treated with EVs or SPLEVs. 4 samples shares lps, treated
- GSE21764 To determine the global gene expression response in murine LPS-induced macrophages treated with a bromodomain inhibitor. 24 samples shares lps, treated
- GSE181643 Oxygen-dependent changes and lysosome activity-dependent changes of gene expression in BMDM after LPS treatment 72 samples shares lps
- GSE181641 Oxygen-dependent changes of gene expression in BMDM after LPS treatment 36 samples shares lps
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.