Crotonate-activated histone H3K14 crotonylation enhances intestinal regeneration after injury [ChIP-seq]
ChIP-seq / ATAC-seq (genome binding and open chromatin) · mouse · 16 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Mus musculus (mouse)
- Samples
- 16 samples: 16 samples, each with a distinct title — no replicated groupsGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Crotonate enhances intestinal regeneration after injury via HBO1-mediated H3K14 crotonylationNature communications · 2025
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE278970_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA1169859 and SRA study SRP537254. Searching any of these in the dataset finder brings you back here.
Any grouping that defines a comparison lives in the sample characteristics, which GEO records separately from the titles.
How we read this: Read from 16 sample titles: 16 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8559007 IgG
- GSM8559008 HBO1
- GSM8559009 127-LI-input
- GSM8559010 129-lLI-input
- GSM8559011 125-LI-input
- GSM8559012 126-LI-input
- GSM8559013 127-LI-K14ac
- GSM8559014 129-LI-K14ac
- GSM8559015 125-LI-K14ac
- GSM8559016 126-LI-K14ac
- GSM8559017 WT1-LI-K14cr
- GSM8559018 WT2-LI-K14cr
- GSM8559019 KO1-LI-K14cr
- GSM8559020 KO2-LI-K14cr
- GSM8559021 D3-WT-ATAC
- GSM8559022 D3-KO-ATAC
- GSE297315 Crotonate-activated histone H3K14 crotonylation enhances intestinal regeneration after injury 41 samples shares h3k14, crotonate-activated, crotonylation, regeneration, intestinal, enhances, histone
- GSE279059 Crotonate-activated histone H3K14 crotonylation enhances intestinal regeneration after injury [RNA-seq] 25 samples shares h3k14, crotonate-activated, crotonylation, regeneration, intestinal, enhances, histone
- GSE241193 P300 Regulates Histone Crotonylation and Preimplantation Embryo Development (ChIP-Seq) 22 samples shares crotonylation, chip-seq, histone
- GSE262919 EZH2 deletion does not impact acinar cell regeneration but restricts progression to pancreatic cancer in mice [ChIP-seq] 36 samples shares regeneration, chip-seq
- GSE254129 Macrophage histone lactylation during ischemia induced-muscle regeneration [CUT&Tag] 16 samples shares regeneration, histone
- GSE275296 H3K36 methylation regulates cell plasticity and regeneration in the intestinal epithelium [cutandtag_enzyme_profiling] 12 samples shares regeneration, intestinal
- GSE338640 Vascular function underlies enhanced intestinal regeneration after FLASH radiation 26 samples shares regeneration, intestinal
- GSE226578 Stem Cell Activity-Coupled Suppression of Endogenous Retrovirus Governs Adult Tissue Regeneration [ChIP-seq/hMeDIP] 25 samples shares regeneration, chip-seq
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.