Transcriptome of adult hearts with cardiomyocyte-specific deficiency of Aars2
RNA-seq (gene expression) · mouse · 20 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 20 samples: 5 conditions, mostly in triplicateGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- PCBP1 regulates alternative splicing of AARS2 in congenital cardiomyopathyNature cardiovascular research · 2026
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE279007_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1169907 and SRA study SRP537252. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 20 samples.
How we read this: 5 replicated groups read from 20 sample titles; they account for 20 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8559571 AWT_P21_1 AWT_P21
- GSM8559572 AKOm6_P21_1 AKOm6_P21
- GSM8559573 AKOm6_P21_2 AKOm6_P21
- GSM8559574 AWT_P21_2 AWT_P21
- GSM8559575 AHet_P21_1 AHet_P21
- GSM8559576 AHet_P21_2 AHet_P21
- GSM8559577 AHet_P21_3 AHet_P21
- GSM8559578 AKOm6_P21_3 AKOm6_P21
- GSM8559579 AWT_P21_3 AWT_P21
- GSM8559580 AWT_P21_4 AWT_P21
- GSM8559581 AWT_P21_5 AWT_P21
- GSM8559582 AKOm6_P21_4 AKOm6_P21
- GSM8559583 AKOm6_P21_5 AKOm6_P21
- GSM8559584 AKOm6_P21_6 AKOm6_P21
- GSM8559585 AKOm6_P14_1 AKOm6_P14
- GSM8559586 AWT_P14_1 AWT_P14
- GSM8559587 AWT_P14_2 AWT_P14
- GSM8559588 AKOm6_P14_2 AKOm6_P14
- GSM8559589 AWT_P14_3 AWT_P14
- GSM8559590 AKOm6_P14_3 AKOm6_P14
- GSE243060 Multi-organ Transcriptome Atlas of a Mouse Model of Relative Energy Deficiency in Sport (REDs) 419 samples shares deficiency
- GSE252926 Influence of GPR35 deficiency on the ileal and macrophage transcriptome 20 samples shares deficiency
- GSE254229 ALS/FTD-linked TBK1 deficiency in microglia induces an aged-like microglial signature and drives social recognition deficits in mice 141 samples shares deficiency
- GSE234911 Transcriptome analysis of cardiac specific depletion of RBPMS and RBPMS2 embryonic hearts 12 samples shares hearts
- GSE267786 Impact of SLC15A4, TASL and TASL2(Gm6377) deficiency on endolysosomal TLR7 and TLR9 responses 95 samples shares deficiency
- GSE260623 Germline ELP1 deficiency sensitizes cerebellar granule neuron progenitors to SHH medulloblastoma [bulkRNA] 91 samples shares deficiency
- GSE281404 Deficiency of the palmitoyl acyltransferase ZDHHC7 modulates gene expression in mice after a mild chronic stress paradigm 80 samples shares deficiency
- GSE243869 KMT2C deficiency enhances HSC mobilization and granulocyte bias in response to G-CSF 78 samples shares deficiency
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.