EPHB2 Drives EMT-Linked Vasculogenic Mimicry and Cervical Cancer Progression via an ERK–ETV4 Transcriptional Program

To investigate the biological function EPHB2 in the cervical cancer, we established hela cell lines in which the EPHB2 gene has been knocked down by the small interfering RNA (siRNA) technique. Two different siRNAs targeting EPHB2 (KD) were used to knockdown EPHB2 expression in hela cells. A scrambled siRNA (NC) was used as a control. For each sample, three independent biological replicates were performed. Then RNA-Seq experiment was performed by Shanghai Biotechnology Corporation (Shanghai, China).