Transcriptional analysis on ischemia-reperfusion injury of mouse normal or steatotic livers
RNA-seq (gene expression) · mouse · 12 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 12 samples: 3 × NS vs 3 × NI vs 3 × HS vs 3 × HIGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Hexosamine biosynthesis dysfunction-induced LIFR N-glycosylation deficiency exacerbates steatotic liver ischemia/reperfusion injuryMetabolism: clinical and experimental · 2025
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE279693_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1174092 and SRA study SRP539114. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 12 samples.
How we read this: 4 replicated groups read from 12 sample titles; they account for 12 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8578226 NS1 NS
- GSM8578227 NS2 NS
- GSM8578228 NS3 NS
- GSM8578229 NI1 NI
- GSM8578230 NI2 NI
- GSM8578231 NI3 NI
- GSM8578232 HS1 HS
- GSM8578233 HS2 HS
- GSM8578234 HS3 HS
- GSM8578235 HI1 HI
- GSM8578236 HI2 HI
- GSM8578237 HI3 HI
- GSE267650 Mouse kidney ischemia-reperfusion injury time course 57 samples shares ischemia-reperfusion, injury
- GSE255837 Dysregulation of the Normal Wound Healing Cascade in Volumetric Muscle Loss Injury 30 samples shares injury, normal
- GSE298751 Prussian blue nanoparticles targeting multiple PANoptosome-mediated PANoptosis for myocardial ischemia-reperfusion injury therapy 15 samples shares ischemia-reperfusion, injury
- GSE274819 Single-cell RNA sequencing of murine kidneys for ischemia-reperfusion induced renal injury and fibrosis 10 samples shares ischemia-reperfusion, injury
- GSE300113 Heterogenous microglial reactivity contrasts with stable vascular transcriptional programs in mouse models of Alzheimer’s, CADASIL, and Traumatic Brain Injury (Main dataset) 59 samples shares injury
- GSE326452 Bulk RNA-seq of mouse brain following closed head injury: role of IL-1R1 signaling 200 samples shares injury
- GSE316925 Transcriptome changes in trigeminal ganglia in the mouse chronic constriction injury of the infraorbital nerve model - role of TRPM3. 136 samples shares injury
- GSE237260 Transcriptome Analysis Reveals Gene Expression Changes in a mouse Model of Hyperoxia-induced acute lung injury 12 samples shares injury
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.