KSRP deficiency attenuates the course of pulmonary aspergil-losis, associated with elevated pathogen-killing activity of in-nate myeloid immune cells
RNA-seq (gene expression) · mouse · 12 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 12 samples: 3 × PMN, WT, biol vs 3 × PMN, KO, biolGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE280203_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1177345 and SRA study SRP540587. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 6 samples.
How we read this: 2 replicated groups read from 12 sample titles; they account for 6 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8591492 PMN, WT, biol. Rep 1 PMN, WT, biol
- GSM8591493 PMN, WT, biol. Rep 1, LPS
- GSM8591494 PMN, WT, biol. Rep 2 PMN, WT, biol
- GSM8591495 PMN, WT, biol. Rep 2, LPS
- GSM8591496 PMN, WT, biol. Rep 3 PMN, WT, biol
- GSM8591497 PMN, WT, biol. Rep 3, LPS
- GSM8591498 PMN, KO, biol. Rep 1 PMN, KO, biol
- GSM8591499 PMN, KO, biol. Rep 1, LPS
- GSM8591500 PMN, KO, biol. Rep 2 PMN, KO, biol
- GSM8591501 PMN, KO, biol. Rep 2, LPS
- GSM8591502 PMN, KO, biol. Rep 3 PMN, KO, biol
- GSM8591503 PMN, KO, biol. Rep 3, LPS
- GSE261642 PLPP1-deficiency-mediated ferroptosis induced by PD-1 signaling impairs antitumor activity of intratumoral CD8+ T cells I 23 samples shares deficiency, activity
- GSE202753 DsbA-L deficiency attenuates LPS-induced acute kidney injury via NF-κB/AP-1 regulation of macrophage polarization 13 samples shares deficiency, attenuates
- GSE280725 Adipose-specific MTP deficiency protects against hepatic steatosis up upregulating PPARα activity 10 samples shares deficiency, activity
- GSE243060 Multi-organ Transcriptome Atlas of a Mouse Model of Relative Energy Deficiency in Sport (REDs) 419 samples shares deficiency
- GSE254229 ALS/FTD-linked TBK1 deficiency in microglia induces an aged-like microglial signature and drives social recognition deficits in mice 141 samples shares deficiency
- GSE267786 Impact of SLC15A4, TASL and TASL2(Gm6377) deficiency on endolysosomal TLR7 and TLR9 responses 95 samples shares deficiency
- GSE260623 Germline ELP1 deficiency sensitizes cerebellar granule neuron progenitors to SHH medulloblastoma [bulkRNA] 91 samples shares deficiency
- GSE281404 Deficiency of the palmitoyl acyltransferase ZDHHC7 modulates gene expression in mice after a mild chronic stress paradigm 80 samples shares deficiency
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.