Adipogenic Transcriptional Regulation Mediated by PARP7 Through NAD+ Sensing Mechanism
ChIP-seq / ATAC-seq (genome binding and open chromatin) · mouse · 65 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Mus musculus (mouse)
- Samples
- 65 samples: 18 conditions, mostly in duplicateGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- NAD (+) Sensing by PARP7 Regulates the C/EBPβ-Dependent Transcription Program in Adipose Tissue In VivobioRxiv : the preprint server for biology · 2025
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE282161_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA1187495 and SRA study SRP545669. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 51 samples.
How we read this: 18 replicated groups read from 65 sample titles; they account for 51 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8635801 Control siRNA Replicate 1 Control siRNA
- GSM8635802 Control siRNA Replicate 2 Control siRNA
- GSM8635803 Parp7 siRNA 1 Replicate 1 Parp7 siRNA 1
- GSM8635804 Parp7 siRNA 1 Replicate 2 Parp7 siRNA 1
- GSM8635805 Parp7 siRNA 2 Replicate 1 Parp7 siRNA 2
- GSM8635806 Parp7 siRNA 2 Replicate 2 Parp7 siRNA 2
- GSM8635807 Input Vehicle Treatment
- GSM8635808 Input MG132 Treatment
- GSM8635809 Input RBN2397 Treatment
- GSM8635810 Vehicle Treatment Replicate 1 Vehicle Treatment
- GSM8635811 Vehicle Treatment Replicate 2 Vehicle Treatment
- GSM8635812 Vehicle Treatment Replicate 3 Vehicle Treatment
- GSM8635813 MG132 Treatment Replicate 1 MG132 Treatment
- GSM8635814 MG132 Treatment Replicate 2 MG132 Treatment
- GSM8635815 MG132 Treatment Replicate 3 MG132 Treatment
- GSM8635816 RBN2397 Treatment Replicate 1 RBN2397 Treatment
- GSM8635817 RBN2397 Treatment Replicate 2 RBN2397 Treatment
- GSM8635818 RBN2397 Treatment Replicate 3 RBN2397 Treatment
- GSM8635819 Control siRNA 0 day Replicate 1 Control siRNA 0 day
- GSM8635820 Control siRNA 0 day Replicate 2 Control siRNA 0 day
- GSM8635821 Control siRNA 0 day Replicate 3 Control siRNA 0 day
- GSM8635822 Control siRNA 0 day Replicate 4 Control siRNA 0 day
- GSM8635823 Parp7 siRNA1 0 day Replicate 1 Parp7 siRNA1 0 day
- GSM8635824 Parp7 siRNA1 0 day Replicate 2 Parp7 siRNA1 0 day
- GSM8635825 Parp7 siRNA1 0 day Replicate 3 Parp7 siRNA1 0 day
- GSM8635826 Parp7 siRNA1 0 day Replicate 4 Parp7 siRNA1 0 day
- GSM8635827 Parp7 siRNA2 0 day Replicate 1 Parp7 siRNA2 0 day
- GSM8635828 Parp7 siRNA2 0 day Replicate 2 Parp7 siRNA2 0 day
- GSM8635829 Parp7 siRNA2 0 day Replicate 3 Parp7 siRNA2 0 day
- GSM8635830 Parp7 siRNA2 0 day Replicate 4 Parp7 siRNA2 0 day
- GSM8635831 Control siRNA 2 day Replicate 1 Control siRNA 2 day
- GSM8635832 Control siRNA 2 day Replicate 2 Control siRNA 2 day
- GSM8635833 Control siRNA 2 day Replicate 3 Control siRNA 2 day
- GSM8635834 Control siRNA 2 day Replicate 4 Control siRNA 2 day
- GSM8635835 Parp7 siRNA1 2 day Replicate 1 Parp7 siRNA1 2 day
- GSM8635836 Parp7 siRNA1 2 day Replicate 2 Parp7 siRNA1 2 day
- GSM8635837 Parp7 siRNA1 2 day Replicate 3 Parp7 siRNA1 2 day
- GSM8635838 Parp7 siRNA1 2 day Replicate 4 Parp7 siRNA1 2 day
- GSM8635839 Parp7 siRNA2 2 day Replicate 1 Parp7 siRNA2 2 day
- GSM8635840 Parp7 siRNA2 2 day Replicate 2 Parp7 siRNA2 2 day
+ 25 more — browse all 65 samples with per-sample file links →
- GSE291544 Roles of chromosomal and gonadal sex in the fetal and placental responses to maternal food restriction in mice [junctional zone/decidua] 60 samples shares nad
- GSE300533 Gonadal and chromosomal sex effects on hepatic transcriptome 48 samples shares nad
- GSE281035 PAR3-mediated coordination of hepatocyte proliferation, maturation, and architecture in liver development and regeneration 128 samples shares mediated
- GSE272849 EOMES establishes mesoderm and endoderm differentiation potential through SWI/SNF-mediated global enhancer remodeling 119 samples shares mediated
- GSE266024 Nrf2-mediated chromatin activation of hyperosmotic response genes attenuates heat-induced renal injury 42 samples shares mediated
- GSE281719 PD-1 Mediated Regulation of Unique Activated CD8+ T Cells by NK Cells in the Submandibular Gland [I15, I16] 60 samples shares mediated
- GSE327880 Neuronal activation triggers rapid biphasic FMRP-mediated translational control linking synaptic and nuclear regulation 51 samples shares mediated
- GSE331176 Phagosome-mediated activation of STING by purine and pyrimidine-based bacterial cyclic dinucleotides 380 samples shares mediated
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.