Nrf2-mediated chromatin activation of hyperosmotic response genes attenuates heat-induced renal injury
ChIP-seq / ATAC-seq (genome binding and open chromatin) · mouse · 42 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Mus musculus (mouse)
- Samples
- 42 samples: 34 distinct titles, 8 of them repeatedGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Nrf2-mediated epigenetic priming of osmoprotective genes enhances cellular adaptation to hyperosmotic stressThe Journal of biological chemistry · 2026
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE266024_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA1105355 and SRA study SRP504398. Searching any of these in the dataset finder brings you back here.
How we read this: Read from 42 sample titles: 34 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8239586 mIMCD3 cells, ATAC_DMSO-2
- GSM8239587 mIMCD3 cells, ATAC_SFN-2
- GSM8239588 mIMCD3 cells, Input-DMSO
- GSM8239589 mIMCD3 cells, Input-SFN
- GSM8239590 mIMCD3 cells, K27ac-DMSO
- GSM8239591 mIMCD3 cells, K27ac-SFN
- GSM8239592 mIMCD3 cells, K27me3_DMSO
- GSM8239593 mIMCD3 cells, K27me3_SFN
- GSM8239594 mIMCD3 cells, K36me3_DMSO
- GSM8239595 mIMCD3 cells, K36me3_SFN
- GSM8239596 mIMCD3 cells, K4me1_DMSO
- GSM8239597 mIMCD3 cells, K4me1_SFN
- GSM8239598 mIMCD3 cells, K4me3_DMSO
- GSM8239599 mIMCD3 cells, K4me3_SFN
- GSM8239600 mIMCD3 cells, K9ac-DMSO
- GSM8239601 mIMCD3 cells, K9ac-SFN
- GSM8239602 mIMCD3 cells, K9me3_DMSO
- GSM8239603 mIMCD3 cells, K9me3_SFN
- GSM8239605 mIMCD3 cells, NFAT5-ChIP-HS-1h-SFN
- GSM8239606 mIMCD3 cells, NFAT5-DMSO
- GSM8239607 mIMCD3 cells, NFAT5-DMSO-1h
- GSM8239608 mIMCD3 cells, NFAT5-SFN
- GSM8239610 mIMCD3 cells, Nrf2_DMSO
- GSM8239611 mIMCD3 cells, Nrf2_DMSO_HS1h
- GSM8239613 mIMCD3 cells, Nrf2_SFN
- GSM8239614 mIMCD3 cells, Nrf2_SFN_HS1h
- GSM8239616 mIMCD3 cells, DMSO_1h_rep1
- GSM8239617 mIMCD3 cells, DMSO_1h_rep2
- GSM8239618 mIMCD3 cells, DMSO_6h_rep1
- GSM8239619 mIMCD3 cells, DMSO_6h_rep2
- GSM8239620 mIMCD3 cells, DMSO_Ctrl_rep1
- GSM8239621 mIMCD3 cells, DMSO_Ctrl_rep2
- GSM8239622 mIMCD3 cells, Nrf2KO_SFN_rep1
- GSM8239623 mIMCD3 cells, Nrf2KO_SFN_rep2
- GSM8239624 mIMCD3 cells, Nrf2KO_SFN_HS1h_rep1
- GSM8239625 mIMCD3 cells, Nrf2KO_SFN_HS1h_rep2
- GSM8239626 mIMCD3 cells, SFN_1h_rep1
- GSM8239627 mIMCD3 cells, SFN_1h_rep2
- GSM8239628 mIMCD3 cells, SFN_6h_rep1
- GSM8239629 mIMCD3 cells, SFN_6h_rep2
+ 2 more — browse all 42 samples with per-sample file links →
- GSE266022 Nrf2-mediated chromatin activation of hyperosmotic response genes attenuates heat-induced renal injury [ChIP-seq] 24 samples shares nrf2-mediated, hyperosmotic, heat-induced, activation, attenuates, chromatin, injury, renal
- GSE232327 Activation of imprinted gene Pw1 promotes cardiac fibrosis after ischemic injury 41 samples shares activation, injury
- GSE297515 Piezo1-dependent activation of stromal cells ignites muscle inflammation in exercise and injury and is associated with inflammaging 90 samples shares activation, injury
- GSE333586 Formylpeptide Receptor Activation Attenuates Renovascular Remodeling in Neurogenic Hypertension (Left Ventricle) 26 samples shares activation, attenuates
- GSE333587 Formylpeptide Receptor Activation Attenuates Renovascular Remodeling in Neurogenic Hypertension (Kidney) 19 samples shares activation, attenuates
- GSE303181 STC-1 Attenuates Scar Formation via PI3K/AKT Pathway Activation and Immune Modulation 12 samples shares activation, attenuates
- GSE292063 Pre-existing epigenetic state and differential NF-kB activation shape type 2 immune cell responses 61 samples shares activation
- GSE244812 Multi-omics profiling of retinal pigment epithelium reveals enhancer-driven activation of RANK-NFATc1 signaling in traumatic proliferative vitreoretinopathy. 54 samples shares activation
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.