GEO series
Non-destructive transcriptomics via vesicular export (NTVE)
GSE283136
Homo sapiens; Mus musculus
Expression profiling by high throughput sequencing
412 samples
2025/09/01
GPL34281GPL34328GPL24676
Summary
Transcriptomics is a valuable technique for multiplexed monitoring of cellular states. Using an engineered RNA adapter, NTVE exports cellular transcripts from inducible human and murine reporter cell lines with high concordance to conventional lysate-derived RNA-seq. NTVE allows monitoring of transcriptome changes in response to genetic and chemical perturbations (Interferon gamma; ASCL1 transactivation) in the same cells over time using standard sequencing workflows.
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Paper (PMID 42034633) ↗
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