5-methylcytosine promotes mRNA export
DNA methylation · human · 44 samples
- What it is
- DNA methylationChemical marks on DNA that help switch genes on or off.
- Organism
- Homo sapiens (human)
- Samples
- 44 samples: 22 conditions, mostly in duplicateGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE93751_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for beta-value tables or raw IDAT files among the supplementary files.
Also filed as BioProject PRJNA362296 and SRA study SRP097125. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 44 samples.
How we read this: 22 replicated groups read from 44 sample titles; they account for 44 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM2461423 HeLa-siCTRL-BS-rep1 HeLa-siCTRL-BS
- GSM2461424 HeLa-siCTRL-BS-rep2 HeLa-siCTRL-BS
- GSM2461425 HeLa-siNSUN2-BS-rep1 HeLa-siNSUN2-BS
- GSM2461426 HeLa-siNSUN2-BS-rep2 HeLa-siNSUN2-BS
- GSM2461427 ALYREF-RIP-BS-rep1 ALYREF-RIP-BS
- GSM2461428 ALYREF-RIP-BS-rep2 ALYREF-RIP-BS
- GSM2461429 Small-Intestine_8W-BS-rep1 Small-Intestine_8W-BS
- GSM2461430 Small-Intestine_8W-BS-rep2 Small-Intestine_8W-BS
- GSM2461431 Heart_8W-BS-rep1 Heart_8W-BS
- GSM2461432 Heart_8W-BS-rep2 Heart_8W-BS
- GSM2461433 Muscle_8W-BS-rep1 Muscle_8W-BS
- GSM2461434 Muscle_8W-BS-rep2 Muscle_8W-BS
- GSM2461435 Brain_8W-BS-rep1 Brain_8W-BS
- GSM2461436 Brain_8W-BS-rep2 Brain_8W-BS
- GSM2461437 Kidney_8W-BS-rep1 Kidney_8W-BS
- GSM2461438 Kidney_8W-BS-rep2 Kidney_8W-BS
- GSM2461439 Liver_8W-BS-rep1 Liver_8W-BS
- GSM2461440 Liver_8W-BS-rep2 Liver_8W-BS
- GSM2461441 Testis_3W-BS-rep1 Testis_3W-BS
- GSM2461442 Testis_3W-BS-rep2 Testis_3W-BS
- GSM2461443 Testis_4W-BS-rep1 Testis_4W-BS
- GSM2461444 Testis_4W-BS-rep2 Testis_4W-BS
- GSM2461445 HeLa-siCTRL-T-rep1 HeLa-siCTRL-T
- GSM2461446 HeLa-siCTRL-T-rep2 HeLa-siCTRL-T
- GSM2461447 HeLa-siNSUN2-T-rep1 HeLa-siNSUN2-T
- GSM2461448 HeLa-siNSUN2-T-rep2 HeLa-siNSUN2-T
- GSM2461449 ALYREF-RIP-rep1 ALYREF-RIP
- GSM2461450 ALYREF-RIP-rep2 ALYREF-RIP
- GSM2461451 Small-Intestine_8W-T-rep1 Small-Intestine_8W-T
- GSM2461452 Small-Intestine_8W-T-rep2 Small-Intestine_8W-T
- GSM2461453 Heart_8W-T-rep1 Heart_8W-T
- GSM2461454 Heart_8W-T-rep2 Heart_8W-T
- GSM2461455 Muscle_8W-T-rep1 Muscle_8W-T
- GSM2461456 Muscle_8W-T-rep2 Muscle_8W-T
- GSM2461457 Brain_8W-T-rep1 Brain_8W-T
- GSM2461458 Brain_8W-T-rep2 Brain_8W-T
- GSM2461459 Kidney_8W-T-rep1 Kidney_8W-T
- GSM2461460 Kidney_8W-T-rep2 Kidney_8W-T
- GSM2461461 Liver_8W-T-rep1 Liver_8W-T
- GSM2461462 Liver_8W-T-rep2 Liver_8W-T
+ 4 more — browse all 44 samples with per-sample file links →
- GSE283136 Non-destructive transcriptomics via vesicular export (NTVE) 412 samples shares export
- GSE250614 Suppression of ERK signalling promotes pluripotent epiblast in the human blastocyst 225 samples shares promotes
- GSE38495 Full-length mRNA-Seq from single-cell levels of RNA and individual circulating tumor cells 121 samples shares mrna
- GSE242098 Med12 ablation promotes anti-tumor function by enhancing tumor intrinsic immunogenicity in Pancreatic ductal adenocarcinoma 114 samples shares promotes
- GSE297591 Cytotoxicity caused by 5-methylcytosine depletion on chromatin-associated RNA by 5-azacytosine in leukemia [RNA-seq] 96 samples shares 5-methylcytosine
- GSE61073 mRNA destabilization is the dominant effect of mammalian microRNAs by the time substantial repression ensues 95 samples shares mrna
- GSE250345 Functional inhibition of core spliceosomal machinery activates intronic premature cleavage and polyadenylation of pre-mRNAs 92 samples shares mrna
- GSE99284 Enhancer reprogramming promotes pancreatic cancer progression and metastasis [ChIP-seq] 90 samples shares promotes
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.