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N6-methyladenosine-Mediated Nuclear Export of Messenger RNA

GSE74397 Homo sapiens; Mus musculus Expression profiling by high throughput sequencing; Other 38 samples Submitted 2017/10/12 Platform GPL13112Platform GPL11154
Summary
N6-methyladenosine (m6A) is the most common internal modification in eukaryotic messenger RNA (mRNA). The effects of this reversible cheimcal modification are mediated in part by methyl-specific RNA binding protein 'readers' of the YTH family. In this study we present the function of YTHDC1 (YT521) in promoting the export of mRNA from the nucleus to the cytoplasm. Additionally, we identify a role for YTHDC1 in exon retention in mouse embryonic stem cells (mESCs).
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Also filed as BioProject PRJNA300279 and SRA study SRP065329. Searching any of these in the dataset finder brings you back here.

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