GEO series
Gene Expression Profiling in Diffuse Large B-Cell Lymphoma (DLBCL) Cell Lines Treated with Selinexor
GSE283388
Homo sapiens
Expression profiling by high throughput sequencing
12 samples
2026/05/12
GPL24676
Summary
This study focuses on the transcriptional response of diffuse large B-cell lymphoma (DLBCL) cell lines, SU-DHL6 and OCI-LY3, to Selinexor treatment. Selinexor, a selective inhibitor of nuclear export (SINE), is known for its antitumor properties. RNA-sequencing was performed to investigate gene expression changes in these DLBCL models after 24 and 48 hours of treatment. The goal is to uncover key molecular pathways and targets influenced by Selinexor, providing insights into its therapeutic potential in DLBCL.
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Paper (PMID 41857699) ↗
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