scRNASeq Data of Tcells in psoriatic skin and healthy skin and TCR analysis of Treg sorted from Psoriatic skin
Single-cell RNA-seq · human · 27 samples
- What it is
- Single-cell RNA-seqGene activity measured in thousands of individual cells, so cell types can be told apart.
- Organism
- Homo sapiens (human)
- Samples
- 27 samples: 27 samples, each with a distinct title — no replicated groupsGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Layilin regulates Treg motility and suppressive capacity in skineLife · 2025
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE283500_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Single-cell studies usually ship their counts as 10x files (matrix.mtx, barcodes.tsv, features.tsv), an .h5 file, or an .rds / .h5ad object that Seurat or Scanpy can open. Look for those among the supplementary files.
Also filed as BioProject PRJNA1194116 and SRA study SRP549380. Searching any of these in the dataset finder brings you back here.
Any grouping that defines a comparison lives in the sample characteristics, which GEO records separately from the titles.
How we read this: Read from 27 sample titles: 27 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8664022 Healthy 1 CD8, GEX
- GSM8664023 Healthy 2 CD8, GEX
- GSM8664024 Healthy 3 CD8, GEX
- GSM8664025 Healthy 4 CD8, GEX
- GSM8664026 Healthy 5 CD45#1, GEX
- GSM8664027 Healthy 5 CD45#2, GEX
- GSM8664028 Healthy 5 CD45#3, GEX
- GSM8664029 PSO 1 CD3neg, GEX
- GSM8664030 PSO 1 CD8, GEX
- GSM8664031 PSO 1 Treg_nonTreg, GEX
- GSM8664032 PSO 2 CD3 neg, GEX
- GSM8664033 PSO 2 nonTreg, GEX
- GSM8664034 PSO 2 TregCD8, GEX
- GSM8664035 PSO 3 CD45pos, GEX
- GSM8664036 PSO 4 CD45pos#1, GEX
- GSM8664037 PSO 4 CD45pos#2, GEX
- GSM8664038 PSO 5 CD45pos#1, GEX
- GSM8664039 PSO 5 CD45pos#2, GEX
- GSM8664040 PSO 1 CD8, TCR
- GSM8664041 PSO 1 Treg_nonTreg, TCR
- GSM8664042 PSO 2 nonTreg, TCR
- GSM8664043 PSO 2 TregCD8, TCR
- GSM8664044 PSO 3 CD45pos, TCR
- GSM8664045 PSO 4 CD45pos#1, TCR
- GSM8664046 PSO 4 CD45pos#2, TCR
- GSM8664047 PSO 5 CD45pos#1, TCR
- GSM8664048 PSO 5 CD45pos#2, TCR
- GSE302214 scRNAseq and TCRseq of tumor infiltrating CD8 T cells from samples 22 samples shares tcr, scrnaseq
- GSE279392 Single-cell RNA and TCR sequencing from skin, blood and cerebral spinal fluid (CSF) samples from Degos disease patients 116 samples shares tcr, skin
- GSE266519 Hematopoietic Stem Cell Transplant and Healthy Donor Single cell RNA-seq (scRNA-seq) combined with T Cell Receptor (TCR) and B Cell Receptor (BCR) sequencing on Timepoints Surrounding SARS-CoV-2 Vaccination and Infection 48 samples shares tcr, healthy
- GSE304309 Single-cell transcriptomic and TCR profiling of peripheral double-positive T cells in healthy human blood [scRNA-seq] 8 samples shares tcr, healthy
- GSE320155 scRNA‑seq of human intra‑hepatic CD4⁺ T cells reveals unique Treg transcriptional identities and two steady‑state tissue‑adaptation programs across healthy and HCC liver samples 60 samples shares healthy, treg
- GSE13355 Gene expression data of skin from psoriatic patients and normal controls 180 samples shares psoriatic, skin
- GSE255918 Functional Dynamics of Dendritic Cells in Response to Cutibacterium acnes Strains Associated with Healthy and Acne-prone Skin 68 samples shares healthy, skin
- GSE334588 Single-cell transcriptomic atlas of adult dermatomyositis, cutaneous lupus erythematosus and healthy skin 48 samples shares healthy, skin
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.