scRNA-seq transcriptomic profiles of cochlear and vestibular hair cells from adult mice [10_weeks_CBAJ]
Single-cell RNA-seq · mouse · 10 samples
- What it is
- Single-cell RNA-seqGene activity measured in thousands of individual cells, so cell types can be told apart.
- Organism
- Mus musculus (mouse)
- Samples
- 10 samples: 6 × Cochlea, 10 weeks, vs 4 × Vestibule, 10 weeks,Groups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Hair Bundle Degeneration is a Key Contributor to Age-Related Vestibular DysfunctionbioRxiv : the preprint server for biology · 2025
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE283534_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Single-cell studies usually ship their counts as 10x files (matrix.mtx, barcodes.tsv, features.tsv), an .h5 file, or an .rds / .h5ad object that Seurat or Scanpy can open. Look for those among the supplementary files.
Also filed as BioProject PRJNA1194472 and SRA study SRP549528. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 10 samples.
How we read this: 2 replicated groups read from 10 sample titles; they account for 10 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8666013 Cochlea, 10 weeks, Bio rep 1 Cochlea, 10 weeks,
- GSM8666014 Cochlea, 10 weeks, Bio rep 2 Cochlea, 10 weeks,
- GSM8666015 Cochlea, 10 weeks, Bio rep 3 Cochlea, 10 weeks,
- GSM8666016 Cochlea, 10 weeks, Bio rep 4 Cochlea, 10 weeks,
- GSM8666017 Cochlea, 10 weeks, Bio rep 5 Cochlea, 10 weeks,
- GSM8666018 Cochlea, 10 weeks, Bio rep 6 Cochlea, 10 weeks,
- GSM8666019 Vestibule, 10 weeks, Bio rep 1 Vestibule, 10 weeks,
- GSM8666020 Vestibule, 10 weeks, Bio rep 2 Vestibule, 10 weeks,
- GSM8666021 Vestibule, 10 weeks, Bio rep 3 Vestibule, 10 weeks,
- GSM8666022 Vestibule, 10 weeks, Bio rep 4 Vestibule, 10 weeks,
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Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.