NIK-Driven IL-23 Production by Myeloid Cells is a Key Factor in the Development of Autoimmune Inflammation [scRNA-seq]
Single-cell RNA-seq · mouse · 2 samples
- What it is
- Single-cell RNA-seqGene activity measured in thousands of individual cells, so cell types can be told apart.
- Organism
- Mus musculus (mouse)
- Samples
- 2 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- NIK-driven IL-23 production by myeloid cells is a key factor in the development of autoimmune inflammationThe Journal of experimental medicine · 2026
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE285714_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Single-cell studies usually ship their counts as 10x files (matrix.mtx, barcodes.tsv, features.tsv), an .h5 file, or an .rds / .h5ad object that Seurat or Scanpy can open. Look for those among the supplementary files.
Also filed as BioProject PRJNA1205695 and SRA study SRP554944. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 2 more — browse all 2 samples with per-sample file links →
- GSE222456 Distinctive CD39+CD9+ lung interstitial macrophages suppress IL-23/Th17-mediated neutrophilic asthma by inhibiting NETosis [scRNA-Seq] 12 samples shares il-23, scrna-seq
- GSE305413 GM-CSF production by immune cells in steady state and autoimmune neuroinflammation mapped using fate-reporting mice 12 samples shares production, autoimmune
- GSE215004 Autoimmune inflammation triggers an HSC-derived trained immunity program in myeloid cells 54 samples shares autoimmune, myeloid
- GSE267123 The transcription factor ZNF469 regulates collagen production in liver fibrosis [MouseFFD] 24 samples shares production, factor
- GSE267124 The transcription factor ZNF469 regulates collagen production in liver fibrosis [MouseMCD] 24 samples shares production, factor
- GSE297249 Unfolded protein response signaling promotes myeloid cell production and cooperates with oncogenic mutation 16 samples shares production, myeloid
- GSE194082 Transforming Growth Factor-β (TGFβ) Prevents Hypertension-Induced Aortic Dissection in Adult Mice via Extracellular Matrix Production (Bulk KO vs. WT SMC) 12 samples shares production, factor
- GSE325544 Loss of TET function in T regulatory cells yields ex-Treg cells biased toward T follicular helper cells, causing autoimmune diseases through autoantibody production 12 samples shares production, autoimmune
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.