Distinctive CD39+CD9+ lung interstitial macrophages suppress IL-23/Th17-mediated neutrophilic asthma by inhibiting NETosis [scRNA-Seq]
Single-cell RNA-seq · mouse · 12 samples
- What it is
- Single-cell RNA-seqGene activity measured in thousands of individual cells, so cell types can be told apart.
- Organism
- Mus musculus (mouse)
- Samples
- 12 samples: 3 × PBS_RNA vs 3 × OVA_RNA vs 3 × Dex_RNA vs 3 × p19_RNAGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Distinctive CD39(+)CD9(+) lung interstitial macrophages suppress IL-23/Th17-mediated neutrophilic asthma by inhibiting NETosisNature communications · 2024
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE222456_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Single-cell studies usually ship their counts as 10x files (matrix.mtx, barcodes.tsv, features.tsv), an .h5 file, or an .rds / .h5ad object that Seurat or Scanpy can open. Look for those among the supplementary files.
Also filed as BioProject PRJNA922146 and SRA study SRP416633. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 12 samples.
How we read this: 4 replicated groups read from 12 sample titles; they account for 12 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM6923642 PBS_RNA_rep1 PBS_RNA
- GSM6923643 PBS_RNA_rep2 PBS_RNA
- GSM6923644 OVA_RNA_rep1 OVA_RNA
- GSM6923645 OVA_RNA_rep2 OVA_RNA
- GSM6923646 OVA_RNA_rep3 OVA_RNA
- GSM6923647 Dex_RNA_rep1 Dex_RNA
- GSM6923648 Dex_RNA_rep2 Dex_RNA
- GSM6923649 p19_RNA_rep1 p19_RNA
- GSM6923650 p19_RNA_rep2 p19_RNA
- GSM6923651 p19_RNA_rep3 p19_RNA
- GSM7500887 PBS_RNA_rep3 PBS_RNA
- GSM7500888 Dex_RNA_rep3 Dex_RNA
- GSE222459 Distinctive CD39+CD9+ lung interstitial macrophages suppress IL-23/Th17-mediated neutrophilic asthma by inhibiting NETosis [bulk RNA-Seq] 6 samples shares il-23, cd39, cd9, th17-mediated, interstitial, neutrophilic, distinctive, macrophages
- GSE296797 CD38+CD93+ microglia and macrophages drive neuroinflammation through glycolysis-histone lactylation axis in multiple sclerosis model mice 17 samples shares cd9, macrophages
- GSE262436 ATV-TfR and ATV-CD98hc biodistribution in the mouse brain 23 samples shares cd9
- GSE246300 Double Negative T Cells Downregulate Intrahepatic Inflammation and Ameliorate Hepatic Ischemia and Reperfusion Injury via CD39-adenosinergic axis [RNA-seq] 18 samples shares cd39
- GSE292555 Microbiota promote enhanced CD39 expression in gamma delta (gd) intraepithelial lymphocytes through the activation of TCR and IL-15 signaling. 16 samples shares cd39
- GSE271184 LAG-3 sustains TOX and regulates the CD94/NKG2-Qa-1b axis to govern exhausted CD8 T cell NK receptor expression and cytotoxicity 16 samples shares cd9
- GSE245107 Microglia modulate the cerebrovascular reactivity through ectonucleotidase CD39 15 samples shares cd39
- GSE263144 Neuron-specific chromatin disruption at CpG islands and aging-related regions in Kabuki syndrome mice [CD90.2+ T cells, RNA-seq] 15 samples shares cd9
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.