The LncRNA 3222401L13Rik Is Upregulated in Aging Astrocytes and Regulates Neuronal Support Function Through Interaction with Npas3 [young]
RNA-seq (gene expression) · mouse · 18 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 18 samples: 6 × young, glia, vs 6 × young, neurons, vs 6 × old, glia,Groups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- lncRNA Glelr modulates microglia inflammatory programs in association with PU.1Neurobiology of disease · 2026
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE286099_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1207923 and SRA study SRP556006. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 18 samples.
How we read this: 3 replicated groups read from 18 sample titles; they account for 18 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8717719 young, glia, replicate 1 young, glia,
- GSM8717720 young, glia, replicate 2 young, glia,
- GSM8717721 young, glia, replicate 3 young, glia,
- GSM8717722 young, glia, replicate 4 young, glia,
- GSM8717723 young, glia, replicate 5 young, glia,
- GSM8717724 young, glia, replicate 6 young, glia,
- GSM8717725 young, neurons, replicate 1 young, neurons,
- GSM8717726 young, neurons, replicate 2 young, neurons,
- GSM8717727 young, neurons, replicate 3 young, neurons,
- GSM8717728 young, neurons, replicate 4 young, neurons,
- GSM8717729 young, neurons, replicate 5 young, neurons,
- GSM8717730 young, neurons, replicate 6 young, neurons,
- GSM8717731 old, glia, replicate 1 old, glia,
- GSM8717732 old, glia, replicate 2 old, glia,
- GSM8717733 old, glia, replicate 3 old, glia,
- GSM8717734 old, glia, replicate 4 old, glia,
- GSM8717735 old, glia, replicate 5 old, glia,
- GSM8717736 old, glia, replicate 6 old, glia,
- GSE263738 Bi-directional immunosuppressive interactions between astrocytes and glioblastoma cells identified by barcoded viral tracing [Mouse Bulk RNA-Seq Dataset of Monocytes, T Cells and Astrocytes 63FG] 57 samples shares interaction, astrocytes
- GSE263737 Bi-directional immunosuppressive interactions between astrocytes and glioblastoma cells identified by barcoded viral tracing [Mouse Bulk RNA-Seq Dataset of Monocytes, T Cells and Astrocytes 5OLJ] 33 samples shares interaction, astrocytes
- GSE269499 Distinct transcriptional programs define a heterogeneous neuronal ensemble for social interaction 28 samples shares interaction, neuronal
- GSE278956 SETD2 contributes to PAF1C interactions with the elongating RNA Pol II and is required for neuronal differentiation [ChIP-Seq] 18 samples shares interaction, neuronal
- GSE240702 Integrated Analysis of lncRNA-miRNA-mRNA Interaction Network in Myocardial Ischemia-Reperfusion Injury During Cardiopulmonary Bypass Surgery in Mouse 12 samples shares interaction, lncrna
- GSE244474 T cell - DAM feedback loop drives CNS inflammation and neurodegenration in SPG15 at an early age via CCR5-CCL5 interaction [CD3+] 1135 samples shares interaction
- GSE255212 Transcriptomic Signatures of WNT-Driven Pathways and Granulosa Cell-Oocyte Interaction during Primordial Follicle Activation 762 samples shares interaction
- GSE262290 Metabolic modeling reveals the aging-associated decline of host–microbiome metabolic interactions in mice 156 samples shares interaction
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.