← BioTransfer GEO Dataset Finder
GEO series

Study of epithelial-mesenchymal transition induced by POU1F1 in normal breast cells

GSE287732 Homo sapiens Expression profiling by high throughput sequencing 6 samples Submitted 2025/05/06 Platform GPL34281
Summary
The failure of treatment to deal with intractable cancer cells has raised the question of whether there is a special population of cells in tumor heterogeneity that exhibit resistant phenotypes that favor micrometastasis and have the potential to cause recurrence. One of the current points of view is that most solid cancers, including breast cancer, are stem cell diseases, and that these CSCs are critical to dissemination and metastasis. Our objective is to study the role of POU1F1 in breast cancer cell plasticity. Specifically, we will evaluate whether POU1F1 could modify the phenotype of normal -epithelial- cells to induce its transformation into CSCs/BCSCs
Published in
POU1F1 induces cancer stem cell-like traits in breast cancer cells by IL-6/JAK2/STAT3 activation and enrichment of ALDH
Avila L, Seoane S, Rodriguez-Gonzalez S et al. · NPJ breast cancer 2026 · PMID 41857068 · doi:10.1038/s41523-026-00929-w
This dataset
Download

Direct links to NCBI, no account and no request form: the whole study as GSE287732_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 6 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1214354 and SRA study SRP559210. Searching any of these in the dataset finder brings you back here.

Samples in this study

The sample list for this study is not cached yet. Press Sort into groups and it will be fetched from NCBI.

+ 6 more — browse all 6 samples with per-sample file links →

Similar datasets

Search all human RNA-seq datasets in GEO →

Share this dataset

Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.